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Biodegradation of p-nitrophenol by engineered strain

التفاصيل البيبلوغرافية
العنوان: Biodegradation of p-nitrophenol by engineered strain
المؤلفون: Jing Xu, Bo Wang, Wen-hui Zhang, Fu-Jian Zhang, Yong-dong Deng, Yu Wang, Jian-Jie Gao, Yong-Sheng Tian, Ri-He Peng, Quan-Hong Yao
المصدر: AMB Express, Vol 11, Iss 1, Pp 1-8 (2021)
بيانات النشر: SpringerOpen, 2021.
سنة النشر: 2021
المجموعة: LCC:Biotechnology
LCC:Microbiology
مصطلحات موضوعية: p-Nitrophenol, Degradation, Multigene metabolic engineering, E. coli, Bioremediation, Biotechnology, TP248.13-248.65, Microbiology, QR1-502
الوصف: Abstract p-Nitrophenol (PNP) is an important environmental pollutant and can causes significant environmental and health risks. Compared with the traditional methods, biodegradation is a useful one to completely remove the harmful pollutants from the environment. Here, an engineered strain was first constructed by introducing PNP biodegradation pathway via the hydroquinone (HQ) pathway into Escherichia coli. In the engineered strain BL-PNP, PNP was completely degraded to β-ketoadipate and subsequently enter the metabolites of multiple anabolic pathways. The high tolerance and rapid degradation ability to PNP enable the engineered strain to have the potential to degrade toxic substances. The engineered strain created in this study can be used as a functional strain for bioremediation of PNP and potential toxic intermediates, and the method of assembling aromatic hydrocarbons metabolic pathway can be used to eradicate nitroaromatic pollutants in the environment.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2191-0855
Relation: https://doaj.org/toc/2191-0855
DOI: 10.1186/s13568-021-01284-8
URL الوصول: https://doaj.org/article/819eabf3646f419c9d2da42c6e5beae9
رقم الأكسشن: edsdoj.819eabf3646f419c9d2da42c6e5beae9
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:21910855
DOI:10.1186/s13568-021-01284-8