دورية أكاديمية
Biodegradation of p-nitrophenol by engineered strain
العنوان: | Biodegradation of p-nitrophenol by engineered strain |
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المؤلفون: | Jing Xu, Bo Wang, Wen-hui Zhang, Fu-Jian Zhang, Yong-dong Deng, Yu Wang, Jian-Jie Gao, Yong-Sheng Tian, Ri-He Peng, Quan-Hong Yao |
المصدر: | AMB Express, Vol 11, Iss 1, Pp 1-8 (2021) |
بيانات النشر: | SpringerOpen, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Biotechnology LCC:Microbiology |
مصطلحات موضوعية: | p-Nitrophenol, Degradation, Multigene metabolic engineering, E. coli, Bioremediation, Biotechnology, TP248.13-248.65, Microbiology, QR1-502 |
الوصف: | Abstract p-Nitrophenol (PNP) is an important environmental pollutant and can causes significant environmental and health risks. Compared with the traditional methods, biodegradation is a useful one to completely remove the harmful pollutants from the environment. Here, an engineered strain was first constructed by introducing PNP biodegradation pathway via the hydroquinone (HQ) pathway into Escherichia coli. In the engineered strain BL-PNP, PNP was completely degraded to β-ketoadipate and subsequently enter the metabolites of multiple anabolic pathways. The high tolerance and rapid degradation ability to PNP enable the engineered strain to have the potential to degrade toxic substances. The engineered strain created in this study can be used as a functional strain for bioremediation of PNP and potential toxic intermediates, and the method of assembling aromatic hydrocarbons metabolic pathway can be used to eradicate nitroaromatic pollutants in the environment. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2191-0855 |
Relation: | https://doaj.org/toc/2191-0855 |
DOI: | 10.1186/s13568-021-01284-8 |
URL الوصول: | https://doaj.org/article/819eabf3646f419c9d2da42c6e5beae9 |
رقم الأكسشن: | edsdoj.819eabf3646f419c9d2da42c6e5beae9 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 21910855 |
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DOI: | 10.1186/s13568-021-01284-8 |