دورية أكاديمية
Assessment of Cutaneous Wound Healing Potential of Hyaluronic Acid and Chitosan in Dogs
| العنوان: | Assessment of Cutaneous Wound Healing Potential of Hyaluronic Acid and Chitosan in Dogs |
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| المؤلفون: | Soheir E. Morsy, Ahmed S. Soliman, Inas N. El-Husseiny, Faten F. Mohammed, AbdulRahman A. Saied, Alsayed A. Mohamed, Asmaa A. Metwally |
| المصدر: | Journal of Advanced Veterinary Research, Vol 13, Iss 8 (2023) |
| بيانات النشر: | Assiut University, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Veterinary medicine |
| مصطلحات موضوعية: | Cutaneous wound healing, Histologic score, Hyaluronic acid, Chitosan, canine, Wound contraction, Veterinary medicine, SF600-1100 |
| الوصف: | Several new topical products have been applied to enhance wound healing and reduce scar formation. The present study aimed to evaluate the potential of the topically applied hyaluronic acid (HA) serum and chitosan (CH) gel for skin wound healing in dogs. Ten adult mongrel dogs were divided into two groups (n = 5 for each). Experimental skin wounds were created in all animals. Eight full-thickness round skin wounds of 2 cm diameter were made on both sides (four for each side) over the dog's dorsal area, where the left side wounds were kept as a control and treated with saline solution only. HA serum and CH gel were used to treat the right-side wounds in the first and second groups, respectively. Wound healing was evaluated clinically and histologically at the 7th, 14th, and 21st days post-treatment. In addition, the tensile strength was measured in both treated wound groups and compared with the control wounds and the normal skin. The results showed that HA-treated wounds exhibited higher wound contraction and better tensile strength compared with CH-treated group. In addition, the histological findings of HA-treated wounds showed marked improvement in histological repair scores compared with CH-treated ones. We concluded that topical HA in a serum formulation provided better skin wound healing compared to CH-treated group. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-6269 2090-6277 |
| Relation: | https://advetresearch.com/index.php/AVR/article/view/1490; https://doaj.org/toc/2090-6269; https://doaj.org/toc/2090-6277 |
| URL الوصول: | https://doaj.org/article/81fccc25a8a94a97bf374ffa9ea15d29 |
| رقم الأكسشن: | edsdoj.81fccc25a8a94a97bf374ffa9ea15d29 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20906269 20906277 |
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