دورية أكاديمية

Associations of changes in lipid metabolism parameters and the severity of COVID-19 infection in Novosibirsk residents

التفاصيل البيبلوغرافية
العنوان: Associations of changes in lipid metabolism parameters and the severity of COVID-19 infection in Novosibirsk residents
المؤلفون: A. A. Karaseva, N. E. Evdokimova, E. V. Stryukova, A. D. Khudyakova, I. I. Logvinenko
المصدر: Российский кардиологический журнал, Vol 27, Iss 9 (2022)
بيانات النشر: «FIRMA «SILICEA» LLC, 2022.
سنة النشر: 2022
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: covid-19, severity, high-density lipoprotein cholesterol, triglycerides, dyslipidemia, atherogenic index of plasma, aip, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Aim. To study the associations of changes in lipid metabolism parameters and the severity of a coronavirus disease 2019 (COVID-19).Material and methods. This cross-sectional study included 270 patients aged 26-84 years (mean age, 53,09±13,22 years) who had COVID-19 within prior two months, which were divided into 3 groups: mild (1, n=128), moderate (2, n=128) and severe (3, n=14) COVID-19. Patients were assessed for body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), total cholesterol, triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C). In addition, atherogenic index of plasma (AIP) was calculated. Statistical processing was performed using the SPSS software package (version 13.0).Results. Patients with severe COVID-19 had significantly higher levels of TG and AIP compared with patients with moderate and mild course. BMI and WC were significantly higher in patients in groups 2 and 3 compared with patients in group 1. In women, BMI and AIP levels were significantly higher in the severe COVID-19 group compared to groups 1 and 2. HDL-C levels were lower in patients with severe COVID-19 compared to those with moderate disease. WHR was higher among men in group 3 compared with group 1.Conclusion. Patients with severe COVID-19 have higher BMI, WC, AIP, TG levels, and lower HD-C levels. The relative odds for severe COVID-19 are associated with increased WC, AIP, TG, and lower HDL-C.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: Russian
تدمد: 1560-4071
2618-7620
Relation: https://russjcardiol.elpub.ru/jour/article/view/4979; https://doaj.org/toc/1560-4071; https://doaj.org/toc/2618-7620
DOI: 10.15829/1560-4071-2022-4979
URL الوصول: https://doaj.org/article/8220dc4601e84934915cbe2356988a23
رقم الأكسشن: edsdoj.8220dc4601e84934915cbe2356988a23
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:15604071
26187620
DOI:10.15829/1560-4071-2022-4979