دورية أكاديمية
Associations of changes in lipid metabolism parameters and the severity of COVID-19 infection in Novosibirsk residents
العنوان: | Associations of changes in lipid metabolism parameters and the severity of COVID-19 infection in Novosibirsk residents |
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المؤلفون: | A. A. Karaseva, N. E. Evdokimova, E. V. Stryukova, A. D. Khudyakova, I. I. Logvinenko |
المصدر: | Российский кардиологический журнал, Vol 27, Iss 9 (2022) |
بيانات النشر: | «FIRMA «SILICEA» LLC, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | covid-19, severity, high-density lipoprotein cholesterol, triglycerides, dyslipidemia, atherogenic index of plasma, aip, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Aim. To study the associations of changes in lipid metabolism parameters and the severity of a coronavirus disease 2019 (COVID-19).Material and methods. This cross-sectional study included 270 patients aged 26-84 years (mean age, 53,09±13,22 years) who had COVID-19 within prior two months, which were divided into 3 groups: mild (1, n=128), moderate (2, n=128) and severe (3, n=14) COVID-19. Patients were assessed for body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), total cholesterol, triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C). In addition, atherogenic index of plasma (AIP) was calculated. Statistical processing was performed using the SPSS software package (version 13.0).Results. Patients with severe COVID-19 had significantly higher levels of TG and AIP compared with patients with moderate and mild course. BMI and WC were significantly higher in patients in groups 2 and 3 compared with patients in group 1. In women, BMI and AIP levels were significantly higher in the severe COVID-19 group compared to groups 1 and 2. HDL-C levels were lower in patients with severe COVID-19 compared to those with moderate disease. WHR was higher among men in group 3 compared with group 1.Conclusion. Patients with severe COVID-19 have higher BMI, WC, AIP, TG levels, and lower HD-C levels. The relative odds for severe COVID-19 are associated with increased WC, AIP, TG, and lower HDL-C. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | Russian |
تدمد: | 1560-4071 2618-7620 |
Relation: | https://russjcardiol.elpub.ru/jour/article/view/4979; https://doaj.org/toc/1560-4071; https://doaj.org/toc/2618-7620 |
DOI: | 10.15829/1560-4071-2022-4979 |
URL الوصول: | https://doaj.org/article/8220dc4601e84934915cbe2356988a23 |
رقم الأكسشن: | edsdoj.8220dc4601e84934915cbe2356988a23 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 15604071 26187620 |
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DOI: | 10.15829/1560-4071-2022-4979 |