دورية أكاديمية

Attempted suicide by Melatonin overdose: Case report and literature review

التفاصيل البيبلوغرافية
العنوان: Attempted suicide by Melatonin overdose: Case report and literature review
المؤلفون: T. Gutierrez Higueras, F. Calera Cortés, A. Trives Muñoz, S. Vicent Forés, S. Sainz De La Cuesta Alonso
المصدر: European Psychiatry, Vol 65, Pp S836-S837 (2022)
بيانات النشر: Cambridge University Press, 2022.
سنة النشر: 2022
المجموعة: LCC:Psychiatry
مصطلحات موضوعية: emergency, melatonine, Suicide, overdose, Psychiatry, RC435-571
الوصف: Introduction Melatonine (N-acetyl-5-methoxytryptamine) is an endogenous neurohormone produced by pineal gland. It is related to sleep-wake circadian rhythms, and nowdays it is sold without prescription as a “natural treatment” for sleep disorders. Most common side effects of melatonin overdose are drowsiness, dizziness, fatigue, headache, confusion, nightmare, hypotension, tachycardia and hypothermia. Supportive measures and control of vital signs are essential for an early discharge of the patient. Objectives To present a case of an 42-year-old woman who was taken to the emergency department after voluntary ingestion of 60 tables of melatonin 2mg (Total amount 120mg), in a suicide attempt. To describe the most common side effects of melatonine overdose a the literature review. Methods Clinical case presentation and retrospective literature review. Results A 42-year-old woman who was taken to the emergency department after voluntary ingestion of 60 tables of melatonin 2mg (Total amount 120mg), about 1 hour before coming, in a suicide attempt. After clinical evalutation, gastric lavage was performed. ang 50g activated charcoal given. Drowiness and mild hypothermia (34ºC) was detected. After 12 hours of vital signs observation the patient was discharged and to psychiatry consultation, where depressive mood disorder and chronic insomnia was diagnosed. Conclusions Melatonin is one of the least toxic medication. Most common side effects of overdose are drowsiness, dizziness, fatigue, headache, confusion, nightmare, hypotension, tachycardia and hypothermia. Supportive measures and control of vital signs are essential for the treatment. Disclosure No significant relationships.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0924-9338
1778-3585
Relation: https://www.cambridge.org/core/product/identifier/S0924933822021666/type/journal_article; https://doaj.org/toc/0924-9338; https://doaj.org/toc/1778-3585
DOI: 10.1192/j.eurpsy.2022.2166
URL الوصول: https://doaj.org/article/8323cacea1a940f982e56d21a5a60d1a
رقم الأكسشن: edsdoj.8323cacea1a940f982e56d21a5a60d1a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:09249338
17783585
DOI:10.1192/j.eurpsy.2022.2166