دورية أكاديمية
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial
| العنوان: | Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial |
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| المؤلفون: | Hao Lai, Yunfeng Li, Yafang He, Fangyao Chen, Baibing Mi, Junqi Li, Jiawen Xie, Guoqing Ma, Jinzhao Yang, Kun Xu, Xia Liao, Yan Yin, Junrong Liang, Liyun Kong, Xinyan Wang, Zhongxia Li, Yuan Shen, Shaonong Dang, Lei Zhang, Qian Wu, Lingxia Zeng, Lin Shi, Xuguang Zhang, Tian Tian, Xin Liu |
| المصدر: | Gut Microbes, Vol 15, Iss 1 (2023) |
| بيانات النشر: | Taylor & Francis Group, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Dietary fiber, probiotics, gut microbiota, functional constipation, nutritional intervention, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | ABSTRACTDietary fibers/probiotics may relieve constipation via optimizing gut microbiome, yet with limited trial-based evidences. We aimed to evaluate the effects of formulas with dietary fibers or probiotics on functional constipation symptoms, and to identify modulations of gut microbiota of relevance. We conducted a 4-week double-blinded randomized placebo-controlled trial in 250 adults with functional constipation. Intervention: A: polydextrose; B: psyllium husk; C: wheat bran + psyllium husk; D: Bifidobacterium animalis subsp. lactis HN019 + Lacticaseibacillus rhamnosus HN001; Placebo: maltodextrin. Oligosaccharides were also included in group A to D. 16S rRNA sequencing was used to assess the gut microbiota at weeks 0, 2, and 4. A total of 242 participants completed the study. No time-by-group effect was observed for bowel movement frequency (BMF), Bristol stool scale score (BSS), and degree of defecation straining (DDS), while BSS showed mean increases of 0.95–1.05 in group A to D (all P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 19490976 1949-0984 1949-0976 |
| Relation: | https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984 |
| DOI: | 10.1080/19490976.2023.2197837 |
| URL الوصول: | https://doaj.org/article/83c9dd8b8ff84fb9bee9dbc9e956d899 |
| رقم الأكسشن: | edsdoj.83c9dd8b8ff84fb9bee9dbc9e956d899 |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 19490976 19490984 |
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| DOI: | 10.1080/19490976.2023.2197837 |