التفاصيل البيبلوغرافية
العنوان:
Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models
المؤلفون:
Samuel Y. Ng , Noriaki Yoshida , Amanda L. Christie , Mahmoud Ghandi , Neekesh V. Dharia , Joshua Dempster , Mark Murakami , Kay Shigemori , Sara N. Morrow , Alexandria Van Scoyk , Nicolas A. Cordero , Kristen E. Stevenson , Maneka Puligandla , Brian Haas , Christopher Lo , Robin Meyers , Galen Gao , Andrew Cherniack , Abner Louissaint , Valentina Nardi , Aaron R. Thorner , Henry Long , Xintao Qiu , Elizabeth A. Morgan , David M. Dorfman , Danilo Fiore , Julie Jang , Alan L. Epstein , Ahmet Dogan , Yanming Zhang , Steven M. Horwitz , Eric D. Jacobsen , Solimar Santiago , Jian-Guo Ren , Vincent Guerlavais , D. Allen Annis , Manuel Aivado , Mansoor N. Saleh , Amitkumar Mehta , Aviad Tsherniak , David Root , Francisca Vazquez , William C. Hahn , Giorgio Inghirami , Jon C. Aster , David M. Weinstock , Raphael Koch
المصدر:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
بيانات النشر:
Nature Portfolio, 2018.
سنة النشر:
2018
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
T- and NK-cell lymphomas (TCL) are a group of lymphoid malignancies characterized by poor prognosis, but the absence of appropriate pre-clinical models has hampered the development of effective therapies. Here the authors establish several pre-clinical models and identify vulnerabilities that could be further exploited to treat patients afflicted by these diseases.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-018-04356-9
URL الوصول:
https://doaj.org/article/ecc83cf960564bd2938fc055d45d8a01
رقم الأكسشن:
edsdoj.83cf960564bd2938fc055d45d8a01
قاعدة البيانات:
Directory of Open Access Journals