دورية أكاديمية
Association between zinc deficiency and aorta stiffness in non-diabetic hemodialysis patients.
العنوان: | Association between zinc deficiency and aorta stiffness in non-diabetic hemodialysis patients. |
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المؤلفون: | Kunihiro Ishioka, Sumi Hidaka, Naoki Fujiwara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Hidekazu Moriya, Takayasu Ohtake, Shuzo Kobayashi |
المصدر: | PLoS ONE, Vol 18, Iss 1, p e0268875 (2023) |
بيانات النشر: | Public Library of Science (PLoS), 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | ObjectivesZinc deficiency (Zn < 60 μg/dL) is known to play an important role for vascular calcification. However, little data is available regarding the association between zinc deficiency and aorta stiffness in dialysis patients. Thus, we studied the relationship between zinc deficiency and aorta stiffness in non-diabetic hemodialysis (HD) patients.MethodsOf 150 patients receiving maintenance HD at our hospital, we included 79 non-diabetic HD patients (age: 70±11 years, 49 men) after excluding 71 diabetic HD patients. Zinc deficiency was defined as Zn ResultsThe zinc deficiency group (ZD group) included 45 patients (57.0%). Compared to the zinc non-deficiency group (ZND group), patients with ZD group were significantly older, higher levels of CRP and hypoalbuminemia. Moreover, they had significantly higher levels of baPWV, and lower levels of ankle-brachial pressure index (ABI) (pConclusionThe study suggested that zinc deficiency may be an independent risk factor for aorta stiffness, even after adjusting for malnutrition and inflammation. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 |
Relation: | https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0268875 |
URL الوصول: | https://doaj.org/article/83ecae1c9a264cc9b13155ab13142e7c |
رقم الأكسشن: | edsdoj.83ecae1c9a264cc9b13155ab13142e7c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 |
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DOI: | 10.1371/journal.pone.0268875 |