دورية أكاديمية
Evaluating the Roles of sCD14 and sCD14-ST in Diagnosing COPD and Predicting an Acute Exacerbation of COPD
| العنوان: | Evaluating the Roles of sCD14 and sCD14-ST in Diagnosing COPD and Predicting an Acute Exacerbation of COPD |
|---|---|
| المؤلفون: | Rui Zhang, Guangxin Sun, Zhengwei Xing, Yuling Bai, Hui Pei, Yulei Gu, Yahui Huang, Xiaofan Zhang, Luanluan Zhang |
| المصدر: | Intensive Care Research, Vol 2, Iss 1-2, Pp 26-33 (2022) |
| بيانات النشر: | Springer, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medical emergencies. Critical care. Intensive care. First aid LCC:Medicine |
| مصطلحات موضوعية: | COPD, sCD14, sCD14-ST, Areas under the ROC curve, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9, Medicine |
| الوصف: | Abstract Aim To evaluate the roles of plasma soluble cluster of differentiation 14 (sCD14) and sCD14 subtype (sCD14-ST) in the diagnosis of chronic obstructive pulmonary disease (COPD) and in the prediction of an acute exacerbation of COPD (AECOPD). Methods We quantified the levels of white blood cell count (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), interleukin (IL)-6, IL-8, sCD14, and sCD14-ST in patients with COPD and healthy controls. The relationships between sCD14 or sCD14-ST and inflammatory markers were analyzed in each group. We used receiver operating characteristics (ROC) curves to evaluate the potential roles of sCD14 and sCD14-ST in the diagnosis of COPD and in predicting AECOPD. Results A total of 62 subjects were recruited, including 15 controls and 47 COPD patients, with the latter including 32 stable COPD and 15 AECOPD. WBC, IL-8, sCD14, and sCD14-ST were significantly higher in COPD than in the controls (all P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2666-9862 |
| Relation: | https://doaj.org/toc/2666-9862 |
| DOI: | 10.1007/s44231-022-00004-5 |
| URL الوصول: | https://doaj.org/article/8456d0bdf5684f9d92c6ba4544521634 |
| رقم الأكسشن: | edsdoj.8456d0bdf5684f9d92c6ba4544521634 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 26669862 |
|---|---|
| DOI: | 10.1007/s44231-022-00004-5 |