دورية أكاديمية
Comparative evaluation of mucin and total protein in periodontal disease before and after nonsurgical periodontal therapy
| العنوان: | Comparative evaluation of mucin and total protein in periodontal disease before and after nonsurgical periodontal therapy |
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| المؤلفون: | J. P. Vishnu, Anju Gautam, Surendra Pratap Mishra, Farhan Durrani, Fouzia Imran, Ekta Kumari |
| المصدر: | Journal of Indian Society of Periodontology, Vol 28, Iss 1, Pp 84-90 (2024) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Dentistry |
| مصطلحات موضوعية: | biomarker, chronic periodontitis, clinical parameters, gingivitis, salivary mucin, total protein, Dentistry, RK1-715 |
| الوصف: | Background: Periodontal ailments cause a quantum leap in the biomarker profile of the saliva. This profile is, in fact, the epiphany of the scale and extent of the disease. Both gingivitis and periodontitis are chronic inflammatory diseases with a step-grade progression. The study aimed to determine the response of the host in these conditions by analyzing concentrations of salivary mucin and total protein activity, before and after nonsurgical periodontal therapy (NSPT). Materials and Methods: Sixty adult subjects were clinically examined and divided into three groups (n = 20) according to the clinical assessment and categorized as Group I (healthy), Group II (gingivitis), and Group III (chronic periodontitis). Whole saliva was collected, and salivary mucin and total protein levels were quantitatively measured at baseline in all the groups and additionally after NSPT in Groups II and III. Results: Levels of mucin and total protein increased in patients with gingivitis and periodontitis. There was a slight decline in mucin levels in periodontitis patients in comparison with the gingivitis group. A positive correlation was found between the respective clinical parameters of both the groups along with their levels of salivary mucin and total protein. It indicated that the response of salivary glands to increase their protective potential caused the change among the groups. Conclusion: Periodontal diseases induce an increase in the levels of mucins and proteins, which is believed as the action of the salivary glands to protect the oral cavity and put off the chaos caused by the microorganisms. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0972-124X 0975-1580 |
| Relation: | https://journals.lww.com/10.4103/jisp.jisp_258_23; https://doaj.org/toc/0972-124X; https://doaj.org/toc/0975-1580 |
| DOI: | 10.4103/jisp.jisp_258_23 |
| URL الوصول: | https://doaj.org/article/848baeee98d64e16ba4e43972ca24e4d |
| رقم الأكسشن: | edsdoj.848baeee98d64e16ba4e43972ca24e4d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 0972124X 09751580 |
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| DOI: | 10.4103/jisp.jisp_258_23 |