دورية أكاديمية
Association between Bone Mineral Density and Fat Mass Independent of Lean Mass and Physical Activity in Women Aged 75 or Older
| العنوان: | Association between Bone Mineral Density and Fat Mass Independent of Lean Mass and Physical Activity in Women Aged 75 or Older |
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| المؤلفون: | Marie Mathieu, Pascale Guillot, Typhaine Riaudel, Anne-Sophie Boureau, Guillaume Chapelet, Céline Brouessard, Laure de Decker, Gilles Berrut |
| المصدر: | Nutrients, Vol 13, Iss 6, p 1994 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | bone mineral density, lean mass, fat mass, osteoporosis, physical activity level, sarcopenia, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | (1) Osteoporosis and sarcopenia are frequent pathologies among the geriatric population. The interlink between these two diseases is supported by their common pathophysiology. The aim is to explore the relationship between bone mineral density (BMD) and body composition in women aged 75 or older. (2) From January 2016 to December 2019, women aged 75 or older of Caucasian ethnicity, who were addressed to perform a biphoton absorptiometry (DXA), were included in this observational study. Femoral neck T-score, lean mass, fat mass, and physical performances were measured. (3) The mean age of 101 patients included was 84.8 (±4.9) years old. Osteoporosis was present in 72% of patients. According to EWGSOP criteria, 37% of patients were sarcopenic. Osteosarcopenia was present in 34% of patients. The femoral neck T-score was significantly associated with fat mass (β = 0.02, 95% CI (0.01; 0.03), p < 0.05) in multivariable analysis. Osteosarcopenic patients had significantly lower fat mass (16.2 kg (±6.8) vs. 23.1 kg (±10.8), p < 0.001) and body mass index (BMI) (20.7 kg/m2 (±2.8) vs. 26.7 kg/m2 (±5.6), p < 0.001). (4) In postmenopausal women, fat mass is estimated to provide hormonal protection. While osteosarcopenia is described as a lipotoxic disease, fat mass and BMI would appear to protect against the risk of osteosarcopenia. This raises questions about the relevance of BMI and DXA. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2072-6643 90754638 |
| Relation: | https://www.mdpi.com/2072-6643/13/6/1994; https://doaj.org/toc/2072-6643 |
| DOI: | 10.3390/nu13061994 |
| URL الوصول: | https://doaj.org/article/d84a907546384adea4c40d7a46e5cd0c |
| رقم الأكسشن: | edsdoj.84a907546384adea4c40d7a46e5cd0c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20726643 90754638 |
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| DOI: | 10.3390/nu13061994 |