دورية أكاديمية
Genetic variants of genital mycoplasmas and their relation to the clinical course of inflammatory diseases of the urogenital system in women
| العنوان: | Genetic variants of genital mycoplasmas and their relation to the clinical course of inflammatory diseases of the urogenital system in women |
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| المؤلفون: | M. R. Rakhmatulina, K. I. Plakhova, A. A. Kubanov |
| المصدر: | Vestnik Dermatologii i Venerologii, Vol 0, Iss 6, Pp 107-113 (2017) |
| بيانات النشر: | State Scientific Center of Dermatovenereology and Cosmetology, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | m. hominis. m. genitalium. ген vaa. ген mg192, m. hominis, m. genitalium, vaa gene, mg192 gene, Dermatology, RL1-803 |
| الوصف: | Goal of the study. To study genetic variability of M. hominis (based on the vaa gene) and M. genitalium (based on the mg192 gene) derived from biological material samples taken from women with different clinical manifestations of inflammatory diseases of the urogenital system and clinically healthy women (for M. hominis). Materials and methods. Genetic variability of twenty M. hominis samples taken from patients with inflammatory diseases of the urogenital system and twenty M. hominis samples taken from patients without clinical and laboratory signs of inflammatory processes of the urogenital system was studied by the sequence analysis method. Genetic variability of eight M. genitalium samples taken from patients with different clinical signs of inflammatory diseases of the urogenital system was also examined by the sequence analysis method. Results. Three genetic variants of M. hominis based on the vaa gene were found; variant I was revealed more often in patients with clinical manifestations of inflammatory diseases (65.0%), and variant II - in clinically healthy women (60.0%). Three phylogenetic M. gentium groups based on the mg192 gene were revealed; two samples were referred to Groups I and II, and four samples were referred to Group III. Samples from each phylogenetic groups were taken from patients with clinical and laboratory manifestations of cervicitis and urethritis. Conclusion. The study data demonstrate a potential effect of the VAA surface protein on the virulence of opportunistic M. hominis pathogens. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Russian |
| تدمد: | 0042-4609 2313-6294 |
| Relation: | https://www.vestnikdv.ru/jour/article/view/88; https://doaj.org/toc/0042-4609; https://doaj.org/toc/2313-6294 |
| DOI: | 10.25208/0042-4609-2014-0-6-107-113 |
| URL الوصول: | https://doaj.org/article/86ef7262e8c1432e8d9771331b5253c0 |
| رقم الأكسشن: | edsdoj.86ef7262e8c1432e8d9771331b5253c0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 00424609 23136294 |
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| DOI: | 10.25208/0042-4609-2014-0-6-107-113 |