دورية أكاديمية
Muscle-invasive urothelial bladder cancer: an update on systemic therapy
| العنوان: | Muscle-invasive urothelial bladder cancer: an update on systemic therapy |
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| المؤلفون: | Hayley Knollman, J. Luke Godwin, Rishi Jain, Yu-Ning Wong, Elizabeth R. Plimack, Daniel M. Geynisman |
| المصدر: | Therapeutic Advances in Urology, Vol 7 (2015) |
| بيانات النشر: | SAGE Publishing, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Urothelial carcinoma is a common malignancy that carries a poor prognosis when the disease includes muscle invasion. Metastatic urothelial carcinoma is almost uniformly fatal. The evidence behind treatment options in the neoadjuvant, adjuvant and metastatic settings are discussed in this manuscript, with a focused review of standard and investigational cytotoxic, targeted, and immunotherapy approaches. We have focused especially on neoadjuvant cisplatin-based therapy (supported by level one evidence) and on novel immunotherapy agents such as checkpoint inhibitors, which have shown great promise in early clinical studies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1756-2872 1756-2880 17562872 |
| Relation: | https://doaj.org/toc/1756-2872; https://doaj.org/toc/1756-2880 |
| DOI: | 10.1177/1756287215607418 |
| URL الوصول: | https://doaj.org/article/87461be9963a4b9e94257975c4368ce6 |
| رقم الأكسشن: | edsdoj.87461be9963a4b9e94257975c4368ce6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17562872 17562880 |
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| DOI: | 10.1177/1756287215607418 |