دورية أكاديمية

Neuroendocrine Carcinoma with Bone Marrow Metastasis: A Case Series

التفاصيل البيبلوغرافية
العنوان: Neuroendocrine Carcinoma with Bone Marrow Metastasis: A Case Series
المؤلفون: Namrata N Rajakumar, Teena D Murthy, Raghavendra H Vijay, Girish Balikai
المصدر: Journal of Clinical and Diagnostic Research, Vol 17, Iss 12, Pp 01-04 (2023)
بيانات النشر: JCDR Research and Publications Private Limited, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
مصطلحات موضوعية: aspirations, biopsy, neuroendocrine carcinomas, skeletal colonisation, Medicine
الوصف: Neuroendocrine Neoplasms (NENs) account for 0.5% of all malignancies. Skeletal colonisation is often regarded as a rare event, and metastasis to the bone marrow occurs in the advanced stage of the disease, carrying a poor prognosis. In this report, the authors present three rare cases of Neuroendocrine Carcinomas (NEC) of the lung, diagnosed among 6766 bone marrow aspirations and biopsies performed at our institution between January 2019 and December 2022, highlighting the rarity of these cases. All three cases (63 years, 56 years and 73 years old male patients) presented to our institute at an advanced stage of the disease, with bone marrow involvement at the time of presentation. They exhibited nonspecific symptoms and had normal haematological parameters. Bone marrow aspiration and biopsy confirmed metastatic NEC. The aim of this case series was to investigate bone marrow involvement in NECs, along with their clinical and radiographic features, treatment, and follow-up. Bone marrow biopsy plays a crucial role not only in diagnosing haematological diseases but also in diagnosing and staging solid tumours. Future prospectives include adopting a multimodal approach for early diagnosis and treatment of NECs.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2249-782X
0973-709X
Relation: https://www.jcdr.net/articles/PDF/18840/66931_CE[Ra1]_F(SS)_QC_PAT.(KK_RN_SHU)_PF1(AKA_KM)_PFA(AKA_KM)_PN(KM).pdf; https://doaj.org/toc/2249-782X; https://doaj.org/toc/0973-709X
DOI: 10.7860/JCDR/2023/66931.18840
URL الوصول: https://doaj.org/article/87a12f3b8e0b42fd9d3c1aa7750e6d05
رقم الأكسشن: edsdoj.87a12f3b8e0b42fd9d3c1aa7750e6d05
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2249782X
0973709X
DOI:10.7860/JCDR/2023/66931.18840