دورية أكاديمية

Modelling of Microfluidic Channel Staging Dielectrophoretic Disjunction of Particles from Living Cells

التفاصيل البيبلوغرافية
العنوان: Modelling of Microfluidic Channel Staging Dielectrophoretic Disjunction of Particles from Living Cells
المؤلفون: M. R. Nisha, K. N. Madhusoodanan
المصدر: Applications of Modelling and Simulation, Vol 3, Iss 2, Pp 119-124 (2019)
بيانات النشر: ARQII PUBLICATION, 2019.
سنة النشر: 2019
المجموعة: LCC:Engineering (General). Civil engineering (General)
LCC:Technology (General)
مصطلحات موضوعية: dielectric particle disjunction, dielectrophoretic force, dna analysis, lab on chip, microfluidic channel, size sensitive separation, Engineering (General). Civil engineering (General), TA1-2040, Technology (General), T1-995
الوصف: Microfluidic channel form fluid manipulating units in Lab on chip systems by performing fluidic operations like transportation, sorting, mixing and separation of liquid samples by saving time and economy in a consistent way. A model of a microfluidic channel meant for separation of blood cells into red blood cells and platelets is designed and modelled using Comsol Multiphysics. The approach exploits the effect of an induced Dielectrophoretic (DEP) force on particles moving through a microfluidic channel driven by non-uniform electric field supplied by serial array microelectrodes. The tragectories of blood cells through the microchannel is modelled by applying an actuating voltage of ±3 V and ±5 V. The non-uniform electric field distribution and the DEP force inside the microchannel causes separation of blood cells. We succeeded to plot the trajectories of separated red blood cells and platelets under the influence of DEP force. The size-sensitive separation of particles from blood cells using a microchannel in the presence of non-uniform electric filed is modelled and simulated by changing the strength of applied electric field.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2600-8084
Relation: http://arqiipubl.com/ojs/index.php/AMS_Journal/article/view/73/58; https://doaj.org/toc/2600-8084
URL الوصول: https://doaj.org/article/89379ce96b44454c83e16ada79bfee7a
رقم الأكسشن: edsdoj.89379ce96b44454c83e16ada79bfee7a
قاعدة البيانات: Directory of Open Access Journals