دورية أكاديمية
More than the SRY: The Non-Coding Landscape of the Y Chromosome and Its Importance in Human Disease
| العنوان: | More than the SRY: The Non-Coding Landscape of the Y Chromosome and Its Importance in Human Disease |
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| المؤلفون: | Emily S. Westemeier-Rice, Michael T. Winters, Travis W. Rawson, Ivan Martinez |
| المصدر: | Non-Coding RNA, Vol 10, Iss 2, p 21 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Genetics |
| مصطلحات موضوعية: | Y chromosome, non-coding RNAs, lncRNAs, miRNAs, circRNAs, Genetics, QH426-470 |
| الوصف: | Historically, the Y chromosome has presented challenges to classical methodology and philosophy of understanding the differences between males and females. A genetic unsolved puzzle, the Y chromosome was the last chromosome to be fully sequenced. With the advent of the Human Genome Project came a realization that the human genome is more than just genes encoding proteins, and an entire universe of RNA was discovered. This dark matter of biology and the black box surrounding the Y chromosome have collided over the last few years, as increasing numbers of non-coding RNAs have been identified across the length of the Y chromosome, many of which have played significant roles in disease. In this review, we will uncover what is known about the connections between the Y chromosome and the non-coding RNA universe that originates from it, particularly as it relates to long non-coding RNAs, microRNAs and circular RNAs. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2311-553X 97982482 |
| Relation: | https://www.mdpi.com/2311-553X/10/2/21; https://doaj.org/toc/2311-553X |
| DOI: | 10.3390/ncrna10020021 |
| URL الوصول: | https://doaj.org/article/c8944de97982482b9d5f882a699ddf9b |
| رقم الأكسشن: | edsdoj.8944de97982482b9d5f882a699ddf9b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2311553X 97982482 |
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| DOI: | 10.3390/ncrna10020021 |