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أعرض في EDS

Vaginal Impact of the Oral Administration of Total Freeze-Dried Culture of LCR 35 in Healthy Women

التفاصيل البيبلوغرافية
العنوان: Vaginal Impact of the Oral Administration of Total Freeze-Dried Culture of LCR 35 in Healthy Women
المؤلفون: J. M. Bohbot, J. M. Cardot
المصدر: Infectious Diseases in Obstetrics and Gynecology, Vol 2012 (2012)
بيانات النشر: Hindawi Limited, 2012.
سنة النشر: 2012
المجموعة: LCC:Gynecology and obstetrics
LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Gynecology and obstetrics, RG1-991, Infectious and parasitic diseases, RC109-216
الوصف: The use of probiotics in the prevention or treatment of some vaginal infections has been the subject of numerous studies. To assess the presence of Lactobacillus casei rhamnosus (LCR35) in the vagina after an oral administration, an open randomised pilot study was conducted on 20 healthy women of child-bearing age. Materials and Methods. 2 groups of 10 women were given a 28-day oral course, that is, at least 108 CFU/day (group 1) or 2×108 CFU/day (group 2) of LCR35. Nugent score and vaginal screening for LCR35 were undertaken before and after 28 days of treatment. Results. The mean Nugent score decreased in group 1 (−0,2) as well as in group 2 (−0,3). 10% of women in group 1 versus 40% of women in group 2 were carrying LCR35 at the end of the trial. Conclusion. LCR35, at the minimal dose of 2 × 108 CFU/day, can return the Nugent score to normal in healthy women of child-bearing age, by means of a well-tolerated vaginal temporary presence. Phase III clinical trials will specify the preventive or curative impact of this orally administered strain on a range of vaginal disorders such as bacterial vaginosis or vulvovaginal candidiasis.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1064-7449
1098-0997
89706935
Relation: https://doaj.org/toc/1064-7449; https://doaj.org/toc/1098-0997
DOI: 10.1155/2012/503648
URL الوصول: https://doaj.org/article/dd897069355f4f78a6befe8e18a01863
رقم الأكسشن: edsdoj.897069355f4f78a6befe8e18a01863
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:10647449
10980997
89706935
DOI:10.1155/2012/503648