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A mammalian methylation array for profiling methylation levels at conserved sequences

التفاصيل البيبلوغرافية
العنوان: A mammalian methylation array for profiling methylation levels at conserved sequences
المؤلفون: Adriana Arneson, Amin Haghani, Michael J. Thompson, Matteo Pellegrini, Soo Bin Kwon, Ha Vu, Emily Maciejewski, Mingjia Yao, Caesar Z. Li, Ake T. Lu, Marco Morselli, Liudmilla Rubbi, Bret Barnes, Kasper D. Hansen, Wanding Zhou, Charles E. Breeze, Jason Ernst, Steve Horvath
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
بيانات النشر: Nature Portfolio, 2022.
سنة النشر: 2022
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Methods to probe DNA methylation in the majority of non-human mammals are lacking. Here the authors developed a Mammalian Methylation Array that includes 36k well-conserved CpGs in mammals which will facilitate cross-species comparisons. They annotate the conserved CpGs in > 200 species. The array allows one to measure methylation in all mammalian species including unsequenced ones.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-022-28355-z
URL الوصول: https://doaj.org/article/8a6ba8ee9691468fa2b7b8d99e1a4571
رقم الأكسشن: edsdoj.8a6ba8ee9691468fa2b7b8d99e1a4571
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-022-28355-z