دورية أكاديمية
Differing Spontaneous Brain Activity in Healthy Adults with Two Different Body Constitutions: A Resting-State Functional Magnetic Resonance Imaging Study
| العنوان: | Differing Spontaneous Brain Activity in Healthy Adults with Two Different Body Constitutions: A Resting-State Functional Magnetic Resonance Imaging Study |
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| المؤلفون: | Ching-Hsiung Liu, Yen-Ying Kung, Tzu-Chen Yeh, Pei-Shan Hsu, Ching-Ju Yang, Chou-Ming Cheng, Hong-Chun Lin, Jen-Lin Yang, Ta-Peng Wu, Ching-Mao Chang, Jen-Chuen Hsieh, Fang-Pey Chen |
| المصدر: | Journal of Clinical Medicine, Vol 8, Iss 7, p 951 (2019) |
| بيانات النشر: | MDPI AG, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | body constitution, magnetic resonance imaging, quality of life, traditional Chinese medicine, Medicine |
| الوصف: | Traditional Chinese medicine (TCM) practitioners assess body constitution (BC) as a treatment basis for maintaining body homeostasis. We investigated patterns in spontaneous brain activity in different BC groups using resting-state functional magnetic resonance imaging (rsfMRI) and determined the relationship between these patterns and quality of life (QOL). Thirty-two healthy individuals divided into two groups (body constitution questionnaire (BCQ)-gentleness [BCQ-G] and BCQ-deficiency [BCQ-D]) based on the body constitution questionnaire (BCQ) underwent rsfMRI to analyze regional homogeneity (ReHo) and the amplitude of low-frequency fluctuation (ALFF). The World Health Organization Quality of Life Instruments (brief edition) scale was used to evaluate the QOL. The BCQ-G group (n = 18) had significantly greater ReHo values in the right postcentral gyrus and lower ALFF values in the brainstem than the BCQ-D group (n = 14). In the BCQ-D group, decreased ReHo of the postcentral gyrus correlated with better physiological functioning; increased ALFF in the brainstem correlated with poor QOL. BCQ-subgroup analysis revealed a nonsignificant correlation between ReHo and Yang deficiency/phlegm and stasis (Phl & STA). Nonetheless, the BCQ-D group showed a positive correlation between ALFF and Phl & STA in the parahippocampus. This study identified differences between BCQ-G and BCQ-D types of healthy adults based on the rsfMRI analysis. The different BCQ types with varied brain endophenotypes may elucidate individualized TCM treatment strategies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2077-0383 89828879 |
| Relation: | https://www.mdpi.com/2077-0383/8/7/951; https://doaj.org/toc/2077-0383 |
| DOI: | 10.3390/jcm8070951 |
| URL الوصول: | https://doaj.org/article/8aa09c42224f4f8982887938367e413d |
| رقم الأكسشن: | edsdoj.8aa09c42224f4f8982887938367e413d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20770383 89828879 |
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| DOI: | 10.3390/jcm8070951 |