دورية أكاديمية
Transcranial direct current stimulation modulates autonomic nervous system and reduces ambulatory blood pressure in hypertensives
| العنوان: | Transcranial direct current stimulation modulates autonomic nervous system and reduces ambulatory blood pressure in hypertensives |
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| المؤلفون: | Bruno Rodrigues, Catarina A. Barboza, Eliezer G. Moura, Gabriela Ministro, Silvia E. Ferreira-Melo, Javier B. Castaño, Olivia M. Ruberti, Rivadávio F. B. De Amorim, Heitor Moreno |
| المصدر: | Clinical and Experimental Hypertension, Vol 43, Iss 4, Pp 320-327 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | hypertension, autonomic modulation, transcranial direct current stimulation (tdcs), ambulatory blood pressure measurement, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Purpose: Transcranial direct current stimulation (tDCS) seems to positively modulate the autonomic nervous system in different clinical conditions and healthy subjects; however, its effects on hypertensive (HTN) patients are not completely known. This study aimed to evaluate the effects of a tDCS or SHAM session (20 min) on blood pressure (BP) and autonomic variables of HTN patients. Materials and Methods: Subjects (n = 13) were randomly submitted to SHAM and tDCS sessions (1 week of washout). Hemodynamic and autonomic variables were measured at baseline, during, and immediately after tDCS or SHAM stimulation (Finometer®, Beatscope). Ambulatory BP measurement (ABPM) was evaluated after the experimental period. Results: Hemodynamic variables were not changed by tDCS, except for the fall in peripheral vascular resistance (Δ = −1696.51 ± 204.65 dyn.s/cm5). After the tDCS, sympathetic modulation was decreased (−61.47%), and vagal modulation was increased (+38.09%). Such acute autonomic changes may have evoked positive results observed in 24 hs-systolic blood pressure (Δ = −8.4 ± 6.2; P = .0022) and 24hs-diastolic blood pressure (Δ = −5.4 ± 4.2; P = .0010) in tDCS subjects compared with that in SHAM. Conclusion: These findings suggest that the tDCS could promote positive acute adjustments on cardiac autonomic control and reduced values on 24-hs BP of HTN patients. More than a proof-of-concept, these results may point out to the future, where brain stimulation (tDCS) can be used to HTN syndromes, such as refractory HTN. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1064-1963 1525-6006 10641963 |
| Relation: | https://doaj.org/toc/1064-1963; https://doaj.org/toc/1525-6006 |
| DOI: | 10.1080/10641963.2021.1871916 |
| URL الوصول: | https://doaj.org/article/ac8b3ce6dbad4fce853bcd02ec34386d |
| رقم الأكسشن: | edsdoj.8b3ce6dbad4fce853bcd02ec34386d |
| قاعدة البيانات: | Directory of Open Access Journals |
PDF full text from Publisher | تدمد: | 10641963 15256006 |
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| DOI: | 10.1080/10641963.2021.1871916 |