دورية أكاديمية
أعرض في EDS

Impact of Aspiration Pneumonia on the Clinical Course of Progressive Supranuclear Palsy: A Retrospective Cohort Study.

التفاصيل البيبلوغرافية
العنوان: Impact of Aspiration Pneumonia on the Clinical Course of Progressive Supranuclear Palsy: A Retrospective Cohort Study.
المؤلفون: Satoshi Tomita, Tomoko Oeda, Atsushi Umemura, Masayuki Kohsaka, Kwiyoung Park, Kenji Yamamoto, Hiroshi Sugiyama, Chiaki Mori, Kimiko Inoue, Harutoshi Fujimura, Hideyuki Sawada
المصدر: PLoS ONE, Vol 10, Iss 8, p e0135823 (2015)
بيانات النشر: Public Library of Science (PLoS), 2015.
سنة النشر: 2015
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Although aspiration pneumonia is the most common complication of progressive supranuclear palsy (PSP), the clinical impact of aspiration pneumonia on disease course and survival has not been fully estimated. Thus, we retrospectively analyzed the prognostic factors and clinical consequences of pneumonia in PSP.The clinical course of patients with aspiration pneumonia was surveyed. The association between baseline clinical features (2 years from disease onset) and latency to the initial development of pneumonia was investigated using survival time and Cox regression analyses.Ninety patients with a clinical diagnosis of PSP were observed for 5.1±3.8 years (mean±SD), and 22 had aspiration pneumonia. Subsequently, 20 patients (91%) had to discontinue oral feeding entirely and 13 (59%) died, whereas, of 68 patients without pneumonia, only three patients (4%) died. Time to initial development of pneumonia was strongly correlated with survival time (Spearman R = 0.92, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC4536232?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0135823
URL الوصول: https://doaj.org/article/8b7d006fd70f48c5b09ef2649b76c596
رقم الأكسشن: edsdoj.8b7d006fd70f48c5b09ef2649b76c596
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0135823