دورية أكاديمية
The relationship between severity of disease and vitamin D levels in children with atopic dermatitis
| العنوان: | The relationship between severity of disease and vitamin D levels in children with atopic dermatitis |
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| المؤلفون: | Ozlem Su, Anıl Gülsel Bahalı, Ayşegül Doğan Demir, Dilek Biyik Ozkaya, Selçuk Uzuner, Didem Dizman, Nahide Onsun |
| المصدر: | Advances in Dermatology and Allergology, Vol 34, Iss 3, Pp 224-227 (2017) |
| بيانات النشر: | Termedia Publishing House, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Dermatology LCC:Internal medicine |
| مصطلحات موضوعية: | atopic dermatitis, vitamin D, SCORing Atopic Dermatitis, Dermatology, RL1-803, Internal medicine, RC31-1245 |
| الوصف: | Introduction : Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin. Aim : To assess the serum level of vitamin D in children with AD and determine its relation to AD severity. Material and methods : Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index. The control group consisted of 37 healthy subjects. Results : The mean serum concentration of 25(OH)D3 in patients with AD was not statistically different from control subjects (p = 0.065). The vitamin D level was significantly lower in moderate and severe AD compared with mild AD, and this difference was statistically significant (p = 0.001 and p = 0.004). Vitamin D showed a negative correlation with serum total IgE levels (p = 0.007). There was no significant correlation between total IgE levels and SCORAD scores (p = 0.089). Conclusions : This study suggests that a low serum vitamin D level is inversely associated with severity of AD in children. Vitamin D has not been included in the routine treatment of AD because of the conflicting results of various studies. Thus, there is a need for more detailed and prospective studies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1642-395X 2299-0046 |
| Relation: | https://www.termedia.pl/The-relationship-between-severity-of-disease-and-vitamin-D-levels-in-children-with-atopic-dermatitis,7,29509,1,1.html; https://doaj.org/toc/1642-395X; https://doaj.org/toc/2299-0046 |
| DOI: | 10.5114/pdia.2017.66054 |
| URL الوصول: | https://doaj.org/article/8bd9847ce5754d8894c11f39bebe5de9 |
| رقم الأكسشن: | edsdoj.8bd9847ce5754d8894c11f39bebe5de9 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1642395X 22990046 |
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| DOI: | 10.5114/pdia.2017.66054 |