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Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style

التفاصيل البيبلوغرافية
العنوان: Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style
المؤلفون: Sara Pfister, Julius Rabl, Thomas Wiegand, Simone Mattei, Alexander A. Malär, Lauriane Lecoq, Stefan Seitz, Ralf Bartenschlager, Anja Böckmann, Michael Nassal, Daniel Boehringer, Beat H. Meier
المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Nackednaviruses and hepatitis B virus (HBV) have a common non-enveloped viral ancestor. While HBV acquired an envelope during evolution, nackednaviruses remained non-enveloped. Here, Pfister et al. apply CryoEM and NMR to characterize the capsid structure of African cichlid nackednavirus (ACNDV) at pH 5.5 and pH 7.5 and show that the capsid structure is very similar to that of HBV.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-023-37068-w
URL الوصول: https://doaj.org/article/8c260d6601c645e1a548bd8179f2151e
رقم الأكسشن: edsdoj.8c260d6601c645e1a548bd8179f2151e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-023-37068-w