Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

التفاصيل البيبلوغرافية
العنوان:	Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice
المؤلفون:	Kanchan Bisht, Kenneth A. Okojie, Kaushik Sharma, Dennis H. Lentferink, Yu-Yo Sun, Hong-Ru Chen, Joseph O. Uweru, Saipranusha Amancherla, Zainab Calcuttawala, Antony Brayan Campos-Salazar, Bruce Corliss, Lara Jabbour, Jordan Benderoth, Bria Friestad, William A. Mills, Brant E. Isakson, Marie-Ève Tremblay, Chia-Yi Kuan, Ukpong B. Eyo
المصدر:	Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:	Nature Portfolio, 2021.
سنة النشر:	2021
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Microglia are involved in debris clearance and synaptic pruning, among other processes. However, their direct interaction with the brain vasculature is less clear. Here, the authors show that capillary-associated microglia (CAMs) regulate vascular tone via PANX1-P2RY12 signalling.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-021-25590-8
URL الوصول:	https://doaj.org/article/8c3b78ae6a934bf382bdde9f4a4a758d
رقم الأكسشن:	edsdoj.8c3b78ae6a934bf382bdde9f4a4a758d
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-021-25590-8