دورية أكاديمية
أعرض في EDS

Adrenal infarction with latent myelodysplastic/myeloproliferative neoplasm, unclassifiable with JAK2V617F mutation

التفاصيل البيبلوغرافية
العنوان: Adrenal infarction with latent myelodysplastic/myeloproliferative neoplasm, unclassifiable with JAK2V617F mutation
المؤلفون: Shunichiro Yasuda, Momoko Chiba, Rie Nishitani, Takako Watanabe
المصدر: Clinical Case Reports, Vol 12, Iss 4, Pp n/a-n/a (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Medicine (General)
مصطلحات موضوعية: adrenal infarction, CHIP, JAK2V617F, myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN‐U), Medicine, Medicine (General), R5-920
الوصف: Key Clinical Message Hematopoietic neoplasms can cause adrenal infarction. In cases of thrombosis occurring at uncommon sites, it is necessary to consider evaluating for the JAK2V617F mutation, even in the absence of notable abnormalities in blood counts. Abstract Adrenal infarction, a rare ailment, has been sporadically linked to hematopoietic neoplasms. A 46‐year‐old male encountered left adrenal infarction, which coincided with a progressive rise in platelet counts. Subsequent diagnosis revealed myelodysplastic/myeloproliferative neoplasm‐unclassifiable, featuring a JAK2V617F mutation. Simultaneously, the patient manifested multiple arteriovenous thromboses, necessitating treatment with edoxaban, aspirin, and hydroxyurea. Following thrombosis resolution, he was transferred to a transplantation center. This report delves into the thrombogenicity linked to the JAK2V617F mutation, while also examining documented instances of adrenal infarction in myeloid neoplasms. We should consider evaluating for JAK2V617F mutation even in cases of thrombosis at unusual sites, including adrenal infarction, even if there are no considerable abnormalities in blood counts.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2050-0904
Relation: https://doaj.org/toc/2050-0904
DOI: 10.1002/ccr3.8729
URL الوصول: https://doaj.org/article/8c72257a456943b387502f94681c3c88
رقم الأكسشن: edsdoj.8c72257a456943b387502f94681c3c88
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20500904
DOI:10.1002/ccr3.8729