Protein folding while chaperone bound is dependent on weak interactions

التفاصيل البيبلوغرافية
العنوان:	Protein folding while chaperone bound is dependent on weak interactions
المؤلفون:	Kevin Wu, Frederick Stull, Changhan Lee, James C. A. Bardwell
المصدر:	Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
بيانات النشر:	Nature Portfolio, 2019.
سنة النشر:	2019
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Spy is an ATP independent chaperone that allows folding of its client protein Im7 while continuously bound to Spy. Here the authors employ kinetics measurements to study the folding of another Spy client protein SH3 and find that Spy’s ability to allow a client to fold while bound is inversely related to how strongly it interacts with that client.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-019-12774-6
URL الوصول:	https://doaj.org/article/8c86c6c179904e2d898f9faec9e90757
رقم الأكسشن:	edsdoj.8c86c6c179904e2d898f9faec9e90757
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-019-12774-6