دورية أكاديمية
Rhabdomyolysis in a patient taking nebivolol
العنوان: | Rhabdomyolysis in a patient taking nebivolol |
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المؤلفون: | Ye Jin Kim, Hae Ri Kim, Hong Jae Jeon, Hyun Jun Ju, Sarah Chung, Dae Eun Choi, Kang Wook Lee, Ki Ryang Na |
المصدر: | Kidney Research and Clinical Practice, Vol 35, Iss 3, Pp 182-186 (2016) |
بيانات النشر: | The Korean Society of Nephrology, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Internal medicine LCC:Specialties of internal medicine |
مصطلحات موضوعية: | β-adrenergic blockers, Myopathies, Nebivolol, Rhabdomyolysis, Internal medicine, RC31-1245, Specialties of internal medicine, RC581-951 |
الوصف: | β Blockers such as propranolol and labetalol are known to induce toxic myopathy because of their partial β2 adrenoceptor agonistic effect. Nebivolol has the highest β1 receptor affinity among β blockers, and it has never been reported to induce rhabdomyolysis until now. We report a patient who developed rhabdomyolysis after changing medication to nebivolol. A 75-year-old woman was admitted to our hospital because of generalized weakness originating 2 weeks before visiting. Approximately 1 month before her admission, her medication was changed from carvedilol 12.5 mg to nebivolol 5 mg. Over this time span, she had no other lifestyle changes causing rhabdomyolysis. Her blood chemistry and whole body bone scan indicated rhabdomyolysis. We considered newly prescribed nebivolol as a causal agent. She was prescribed carvedilol 12.5 mg, which she was previously taking, instead of nebivolol. She was treated by hydration and urine alkalization. She had fully recovered and was discharged. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Korean |
تدمد: | 2211-9132 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2211913215300024; https://doaj.org/toc/2211-9132 |
DOI: | 10.1016/j.krcp.2015.09.003 |
URL الوصول: | https://doaj.org/article/8cbc0f950a4e4f3ca199a8bf633731a6 |
رقم الأكسشن: | edsdoj.8cbc0f950a4e4f3ca199a8bf633731a6 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22119132 |
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DOI: | 10.1016/j.krcp.2015.09.003 |