دورية أكاديمية
Acute acquired toxoplasmosis: clinical-laboratorial aspects and ophthalmologic evaluation in a cohort of immunocompetent patients
| العنوان: | Acute acquired toxoplasmosis: clinical-laboratorial aspects and ophthalmologic evaluation in a cohort of immunocompetent patients |
|---|---|
| المؤلفون: | ES Neves, LN Bicudo, AL Curi, E Carregal, WF Bueno, RG Ferreira, MR Amendoeira, E Benchimol, O Fernandes |
| المصدر: | Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 2, Pp 393-396 (2009) |
| بيانات النشر: | Fundação Oswaldo Cruz (FIOCRUZ), 2009. |
| سنة النشر: | 2009 |
| المجموعة: | LCC:Microbiology LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | toxoplasmosis, retinochoroiditis, hepatomegaly, morbidity, Toxoplasma gondii, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Most cases of acute acquired toxoplasmosis (AAT) are oligosymptomatic and self-limited. Therefore, these infections rarely indicate treatment. Prospective studies of AAT patients are rare in the medical literature. The frequency of systemic manifestations has not been sufficiently studied. In order to search for risks factors for systemic and ocular involvement, 37 patients were submitted to a diagnostic investigative protocol. The most frequent findings were lymph node enlargement (94.6%), asthenia (86.5%), headache (70.3%), fever (67.6%) and weight loss (62.2%). Hepatomegaly and/or splenomegaly were present in 21.6% of cases (8/37). Liver transaminases were elevated in 11 patients (29.7%) and lactic dehydrogenase in 17 patients (45.9%). Anaemia was found in four patients (10.8%), leucopoenia in six patients (16.2%), lymphocytosis in 14 patients (37.8%) and thrombocytopenia in one patient (2.7%). Fundoscopic examination revealed retinochoroiditis in four patients (10.8%). No statistical association was found between any one morbidity and retinochoroiditis. Nevertheless, a significant association was found between the presence of more than eight morbidity features at evaluation and long-lasting disease. An ideal diagnostic protocol for AAT would include evidence of systemic involvement. Such a protocol could be used when planning treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0074-0276 1678-8060 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000200039; https://doaj.org/toc/0074-0276; https://doaj.org/toc/1678-8060 |
| DOI: | 10.1590/S0074-02762009000200039 |
| URL الوصول: | https://doaj.org/article/a8ce396cd03d4457ab5f2deb1665329c |
| رقم الأكسشن: | edsdoj.8ce396cd03d4457ab5f2deb1665329c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 00740276 16788060 |
|---|---|
| DOI: | 10.1590/S0074-02762009000200039 |