دورية أكاديمية
Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series
العنوان: | Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series |
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المؤلفون: | Roman S. Pavelyev, Rusalia M. Vafina, Konstantin V. Balakin, Oleg I. Gnezdilov, Aleksey B. Dobrynin, Olga A. Lodochnikova, Rashid Z. Musin, Galina A. Chmutova, Svetlana A. Lisovskaya, Liliya E. Nikitina |
المصدر: | Journal of Chemistry, Vol 2018 (2018) |
بيانات النشر: | Wiley, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Chemistry |
مصطلحات موضوعية: | Chemistry, QD1-999 |
الوصف: | Synthesis of β-hydroxysulfides of 1,3-dioxepane series and their further functionalization were performed. Chiral β-hydroxysulfides were separated into enantiomers using enzymatic acylation by lipase PS. Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2090-9063 2090-9071 |
Relation: | https://doaj.org/toc/2090-9063; https://doaj.org/toc/2090-9071 |
DOI: | 10.1155/2018/3589342 |
URL الوصول: | https://doaj.org/article/e8d01ec389d74868938a8c8626f57210 |
رقم الأكسشن: | edsdoj.8d01ec389d74868938a8c8626f57210 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20909063 20909071 |
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DOI: | 10.1155/2018/3589342 |