Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

التفاصيل البيبلوغرافية
العنوان:	Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans
المؤلفون:	Lotte C. Houtepen, Christiaan H. Vinkers, Tania Carrillo-Roa, Marieke Hiemstra, Pol A. van Lier, Wim Meeus, Susan Branje, Christine M. Heim, Charles B. Nemeroff, Jonathan Mill, Leonard C. Schalkwyk, Menno P. Creyghton, René S. Kahn, Marian Joëls, Elisabeth B. Binder, Marco P. M. Boks
المصدر:	Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
بيانات النشر:	Nature Portfolio, 2016.
سنة النشر:	2016
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Exposure to childhood trauma is a major risk factor for the development of almost all psychiatric disorders. By epigenome-wide studies, here, Houtepen et al. show that DNA methylation at a locus in the Kit ligand gene (KITLG) mediates the relationship between childhood trauma and cortisol stress reactivity.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/ncomms10967
URL الوصول:	https://doaj.org/article/8d086f36e6654c299d12aa96eafaf3c5
رقم الأكسشن:	edsdoj.8d086f36e6654c299d12aa96eafaf3c5
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/ncomms10967