دورية أكاديمية
Glioma stem cells and their microenvironment: A narrative review on docking and transformation
| العنوان: | Glioma stem cells and their microenvironment: A narrative review on docking and transformation |
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| المؤلفون: | Wenyu Zhu, Hua Chen, Ke Yan, Jie Wu, Yaodong Zhao, Qiang Huang |
| المصدر: | Glioma, Vol 5, Iss 1, Pp 12-19 (2022) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | cytomegalovirus infects glioma, embryonic stem cell, epithelial-stromal transformation of glioma, glioblastoma, glioma, glioma microenvironment, glioma stem cells, glioma stem cell niche, mesenchymal stem cells, remodeling of glioma microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Significant new progress was made 10 years ago in the hypothesis that neuroglial cells, neural stem cells, and glioma stem cells (GSCs) depend on the tumor microenvironment (TME) transformation: (1) Because GSCs also have heterogeneity, they are a state, not an entity. (2) The importance of the border niche among many tumor niches is emphasized because it is a shelter for tumor resistance to radiotherapy and chemotherapy. (3) The plasticity of GSCs and TME cells allows TME cells to become GSC-initiating cells. (4) Future development will entail a close interaction between high-throughput molecular biology and artificial intelligence. In this review, we summarize recent advances in GSCs and their microenvironment from the following three aspects: the constantly updated of concept of stem cells, the concept of TME and niche, and the plasticity of GSCs and TME cells. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2589-6113 2589-6121 |
| Relation: | http://www.jglioma.com/article.asp?issn=2589-6113;year=2022;volume=5;issue=1;spage=12;epage=19;aulast=Zhu; https://doaj.org/toc/2589-6113; https://doaj.org/toc/2589-6121 |
| DOI: | 10.4103/glioma.glioma_5_22 |
| URL الوصول: | https://doaj.org/article/8d12611a7dd94376a8cfb2e586edff97 |
| رقم الأكسشن: | edsdoj.8d12611a7dd94376a8cfb2e586edff97 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25896113 25896121 |
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| DOI: | 10.4103/glioma.glioma_5_22 |