دورية أكاديمية
Convergent synthesis of the pentasaccharide repeating unit of the biofilms produced by Klebsiella pneumoniae
| العنوان: | Convergent synthesis of the pentasaccharide repeating unit of the biofilms produced by Klebsiella pneumoniae |
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| المؤلفون: | Arin Gucchait, Angana Ghosh, Anup Kumar Misra |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 431-436 (2019) |
| بيانات النشر: | Beilstein-Institut, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | beta-D-mannoside, biofilms, D-glucuronic acid, glycosylation, Klebsiella pneumoniae, pentasaccharide, polysaccharide, Science, Organic chemistry, QD241-441 |
| الوصف: | A pentasaccharide repeating unit containing α-linked D-glucuronic acid, β-linked D-mannose, corresponding to the repeating unit of biofilms produced by Klebsiella pneumoniae, has been synthesized using a stereoselective [2 + 3] convergent glycosylation strategy. The β-D-mannosidic moiety has been synthesized using a D-mannose-derived thioglycoside by a two-step activation process. Late stage TEMPO-mediated oxidation of the pentasaccharide derivative using phase-transfer reaction conditions furnished the target compound in satisfactory yield. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.15.37 |
| URL الوصول: | https://doaj.org/article/c8d7e3fbac7f443295f3970e8358c187 |
| رقم الأكسشن: | edsdoj.8d7e3fbac7f443295f3970e8358c187 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
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| DOI: | 10.3762/bjoc.15.37 |