دورية أكاديمية
Application of cardiovascular risk scales to identify carotid atherosclerosis in patients with rheumatoid arthritis
| العنوان: | Application of cardiovascular risk scales to identify carotid atherosclerosis in patients with rheumatoid arthritis |
|---|---|
| المؤلفون: | Elena V. Gerasimova, Tatiana V. Popkova, Daria A. Gerasimova, Svetlana I. Glukhova, Evgeny L. Nasonov, Aleksander M. Lila |
| المصدر: | Терапевтический архив, Vol 93, Iss 5, Pp 561-567 (2021) |
| بيانات النشر: | "Consilium Medicum" Publishing house, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | rheumatoid arthritis, cardiovascular diseases, score, reynolds risk score, assign, qrisk3, ers-ra, Medicine |
| الوصف: | Aim. To evaluate the cardiovascular risk (CVR) and analyze its relationship with detection of early carotid artery atherosclerotic lesion in patients with rheumatoid arthritis (RA). Materials and methods. One hundred and nine RA patients aged 45 to 60 without established cardiovascular diseases (CVD) were included in the study. The median age was 52 [48; 54] years, duration of RA was 120 [36; 204] months, DAS28 was 4.7 [3.5; 5.6] points. CVD risk was calculated with mSCORE, Reynolds Risk Score (RRS), ASSIGN, QRISK3, ERS-RA scales and Carotid Artery Doppler Ultrasound Exam was performed for all patients. Results. High risk was found in 5, 5, 14, 6, and 38% of patients according to mSCORE, RRS, ASSIGN, QRISK3, ERS-RA scales, respectively. Atherosclerotic plaques of carotid arteries were found in 30% of patients. It was found that carotid intima-media thickness is correlated to all CVR calculators, age, systolic and diastolic blood pressure, cholesterol, erythrocyte sedimentation rate, interleukin-6 levels. The sensitivity and specificity of the CVR algorithms in prognostication of atherosclerotic carotid artery lesions were 73 and 67% for mSCORE, 64 and 63% for RRS, 64 and 56% for ASSIGN, 73 and 49% for QRISK3, respectively, p0.05 in all cases, 67 and 50% for ERS-RA, p=0.06. Conclusion. RRS, mSCORE, ASSIGN, QRISK3 calculators equally predict atherosclerotic carotid artery damage in RA patients. The optimal ratio of specificity and sensitivity is shown for the mSCORE scale. Stratification of CVR in RA patients should include assessment of the carotid intima-media thickness. To identify CVR in RA patients, the most informative methods are mSCORE calculation and carotid intima-media thickness determination. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 0040-3660 2309-5342 00403660 |
| Relation: | https://ter-arkhiv.ru/0040-3660/article/viewFile/71508/52264; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342 |
| DOI: | 10.26442/00403660.2021.05.200787 |
| URL الوصول: | https://doaj.org/article/8dfe1e024cf545fd8562158ed61adeb5 |
| رقم الأكسشن: | edsdoj.8dfe1e024cf545fd8562158ed61adeb5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 00403660 23095342 |
|---|---|
| DOI: | 10.26442/00403660.2021.05.200787 |