دورية أكاديمية
Update on diagnosis and management of refractory corneal infections
| العنوان: | Update on diagnosis and management of refractory corneal infections |
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| المؤلفون: | Shweta Agarwal, Tanveer A Khan, Murugesan Vanathi, Bhaskar Srinivasan, Geetha Iyer, Radhika Tandon |
| المصدر: | Indian Journal of Ophthalmology, Vol 70, Iss 5, Pp 1475-1490 (2022) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | adjunctive therapy, corneal ulcers, refractory infectious keratitis, Ophthalmology, RE1-994 |
| الوصف: | Infectious keratitis is a medical emergency resulting in significant visual morbidity. Indiscriminate use of antimicrobials leading to the emergence of resistant or refractory microorganisms has further worsened the prognosis. Coexisting ocular surface diseases, delay in diagnosis due to inadequate microbiological sample, a slow-growing/virulent organism, or systemic immunosuppressive state all contribute to the refractory response of the ulcer. With improved understanding of these varied ocular and systemic factors contributing to the refractory nature of the microbes, role of biofilm formation and recent research on improving the bioavailability of drugs along with the development of alternative therapies have helped provide the required multidimensional approach to effectively diagnose and manage cases of refractory corneal ulcers and prevent corneal perforations or further dissemination of disease. In this review, we explore the current literature and future directions of the diagnosis and treatment of refractory keratitis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0301-4738 1998-3689 |
| Relation: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=5;spage=1475;epage=1490;aulast=Agarwal; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689 |
| DOI: | 10.4103/ijo.IJO_2273_21 |
| URL الوصول: | https://doaj.org/article/eae8efa6dce747419be25dccb2f9b3ca |
| رقم الأكسشن: | edsdoj.8efa6dce747419be25dccb2f9b3ca |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03014738 19983689 |
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| DOI: | 10.4103/ijo.IJO_2273_21 |