دورية أكاديمية

The Public health problem and resistant bacteria in lowand middle-income countries

التفاصيل البيبلوغرافية
العنوان: The Public health problem and resistant bacteria in lowand middle-income countries
المؤلفون: Alina FERDOHLEB, Oana-Simina IACONI, Greta BALAN, Lucia GALBEN, Lukasz DZIEWIT, Carles M. BORREGO
المصدر: One Health & Risk Management, Vol 5, Iss 1, Pp 34-42 (2024)
بيانات النشر: Asociatia de Biosiguranta si Biosecuritate, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: antimicrobial resistance, bacteria, lmics, susceptibility testing, bacteriophages, water treatment, Medicine, Science
الوصف: Introduction. Antimicrobial resistance has been declared a major public health problem. As a result of excessive antibiotic usage, it became an environmental issue. This problem is now more visible in Low-and Middle-Income Countries, where it increases the social burden. One of the newest methods to fight antimicrobial-resistant bacteria (ARB) is by using bacteriophages. Aim Identification and characterization of possible phage targets from waterland. Material and methods The strains were obtained from inpatients and identified using VITEK 2 Compact and culture. The resistance profiles were determined by the disk diffusion method and interpreted according to EUCAST methodology. The presence of resistance mechanisms was checked by phenotypic testing. 31 bacterial strains were selected for research. Results K. pneumoniae, P. aeruginosa, Acinetobacter spp., S. aureus, E. coli and Enterococcus spp. were identified. The resistance profile of the isolates showed: 61,5% of K. pneumoniae isolates were PDR, and 23,1% were susceptible only to Carbapenems. E. coli strains were XDR, 71,4% of P. aeruginosa and 75% of Acinetobacter spp. were PDR bacteria. The susceptibility profile of S. aureus strains showed that 3/4 were resistant to Cephalosporins and Fluoroquinolones. Conclusions. Combating the AMR phenomenon starts with knowing the pathogens present in the environment. This study is the cornerstone for further research that will ultimately lead to finding suitable phages for water treatment in Moldova, hoping they will reduce the economic and social burden and also, environmental contamination.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
French
Romanian; Moldavian; Moldovan
Russian
تدمد: 2587-3458
2587-3466
Relation: https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/570; https://doaj.org/toc/2587-3458; https://doaj.org/toc/2587-3466
DOI: 10.38045/ohrm.2024.1.05
URL الوصول: https://doaj.org/article/dece8f38661145d9a0f1bee50664bc9e
رقم الأكسشن: edsdoj.8f38661145d9a0f1bee50664bc9e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:25873458
25873466
DOI:10.38045/ohrm.2024.1.05