دورية أكاديمية

THE EFFECTS OF ENALAPRIL ON EXPERIMENTAL GENTAMICIN NEPHROTOXICITY

التفاصيل البيبلوغرافية
العنوان: THE EFFECTS OF ENALAPRIL ON EXPERIMENTAL GENTAMICIN NEPHROTOXICITY
المؤلفون: Milan Ćirić, Mirjana Radenković, Milkica Nešić, Snežana Cekić, Nela Puškaš, Nenad Stoiljković, Milica Veljković, Boris Đinđić
المصدر: Acta Medica Medianae, Vol 53, Iss 2, Pp 16-21 (2014)
بيانات النشر: University in Nis, Faculty of Medicine, 2014.
سنة النشر: 2014
المجموعة: LCC:Medicine
مصطلحات موضوعية: Enalapril, Gentamicin nephrotoxicity, epithel desquamation, proximal tubules, rat, Medicine
الوصف: We examined the effects of Enalapril on glomerular and tubular renal changes induced by Gentamicin. The control group of Wistar rats was treated by physiological solvent. The second group was treated with Gentamicin in the dose of 100 mg/kg b.m. The third group was treated with Gentamicin in the same dose and with Enalapril in the dose of 1 mg/kg b.m. The levels of sodium, potassium, urea and creatinine from the blood samples were analyzed. The kidneys were taken out and processed in a standard histological way, by haematoxilin eosin and periodic acid shift coloring for light microscopy. Our results showed that simultaneous treatment with Gentamicin and Enalapril intensified and extensified the nephron morphological changes which corresponded to biochemical changes. The decrease of sodium serum concentration (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0365-4478
1821-2794
Relation: http://publisher.medfak.ni.ac.rs/2014-html/2-broj/Milan%20Ciric-%20Enalapril.pdf; https://doaj.org/toc/0365-4478; https://doaj.org/toc/1821-2794
DOI: 10.5633/amm.2014.0203
URL الوصول: https://doaj.org/article/8f3d8680db564d7890cd46b98ba53b65
رقم الأكسشن: edsdoj.8f3d8680db564d7890cd46b98ba53b65
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:03654478
18212794
DOI:10.5633/amm.2014.0203