دورية أكاديمية
Multidrug resistant tuberculosis in HIV positive patients and its effect on Interleukin-2 and Interferon-γ
| العنوان: | Multidrug resistant tuberculosis in HIV positive patients and its effect on Interleukin-2 and Interferon-γ |
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| المؤلفون: | Abdulahi Isiyaku, Taysir Hafiz |
| المصدر: | Microbes and Infectious Diseases, Vol 3, Iss 3, Pp 615-624 (2022) |
| بيانات النشر: | Zagazig University, Faculty of Medicine, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | cytokines, ds-tb, mdr-tb, hiv, mycobacterium tuberculosis, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Background: This is a case control study aimed to detect plasma level of interleukin-2 (IL-2) and interferon-gamma (IFN-γ) cytokines in multidrug resistant tuberculosis (MDR-TB) co-infected with human immunodeficiency virus (HIV) patients and multidrug resistant tuberculosis (MDR-TB) monoinfected patients. Methods: This study determined the differences in plasma concentrations of pro-inflammatory (IL-2 and IFN-γ) cytokines in MDR-TB co-infected with HIV patients and MDR-TB monoinfected patients. Plasma levels of IL-2 and IFN-γ were measured in 130 participants (comprising 15 MDR-TB/HIV co-infected treatment naïve patients, 15 MDR-TB/HIV co-infected treatment experienced patients, 20 MDR-TB monoinfected treatment naïve patients, 20 MDR-TB monoinfected treatment experienced patients, 20 drug susceptible tuberculosis (DS-TB) co-infected with HIV treatment experienced patients and 40 apparently healthy control groups) using enzyme-linked immunosorbant assay (ELISA). Results: Shows that the mean plasma level of IL-2 (210.02 ± 59.27 pg/ml) measured in MDR-TB co-infected with HIV treatment-naïve patients (group 1a) was significantly (p < /em> |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2682-4132 2682-4140 |
| Relation: | https://mid.journals.ekb.eg/article_248896_8c6c6d446af421264fe08db7c5836a88.pdf; https://doaj.org/toc/2682-4132; https://doaj.org/toc/2682-4140 |
| DOI: | 10.21608/mid.2022.139946.1317 |
| URL الوصول: | https://doaj.org/article/d8f9e508d0d2484586237e7191927132 |
| رقم الأكسشن: | edsdoj.8f9e508d0d2484586237e7191927132 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26824132 26824140 |
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| DOI: | 10.21608/mid.2022.139946.1317 |