دورية أكاديمية
أعرض في EDS

Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV

التفاصيل البيبلوغرافية
العنوان: Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV
المؤلفون: Ling Ao, Ting Lu, Yu Cao, Zhiwei Chen, Yuting Wang, Zisheng Li, Xingqian Ren, Pan Xu, Mingli Peng, Min Chen, Gaoli Zhang, Dejuan Xiang, Dachuan Cai, Peng Hu, Xiaofeng Shi, Dazhi Zhang, Hong Ren
المصدر: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1126-1134 (2022)
بيانات النشر: Taylor & Francis Group, 2022.
سنة النشر: 2022
المجموعة: LCC:Infectious and parasitic diseases
LCC:Microbiology
مصطلحات موضوعية: SARS-CoV-2 vaccine, COVID-19, PLWH, safety, humoral immune response, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
الوصف: It is important to know the safety and efficacy of vaccination in immunocompromised people living with HIV (PLWH), but currently, there is limited data on the inactivated SARS-CoV-2 vaccines’ safety and immune responses in PLWH. In this prospective observational study, 139 PLWH and 120 healthy controls were enrolled and monitored for 21–105 days after a two-dose vaccination. The safety, anti-receptor binding domain IgG (anti-RBD-IgG) and anti-spike-IgG responses, and RBD-specific memory B cell (MBC) responses were evaluated. The overall adverse events within seven days were reported in 12.9% (18/139) of PLWH and 13.3% (16/120) of healthy controls. No serious adverse events occurred in both groups. Overall, the seroprevalence of anti-RBD-IgG in PLWH was significantly decreased (87.1% vs. 99.2%; p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 22221751
2222-1751
Relation: https://doaj.org/toc/2222-1751
DOI: 10.1080/22221751.2022.2059401
URL الوصول: https://doaj.org/article/c9045476d42849bbae2078e34d3cc143
رقم الأكسشن: edsdoj.9045476d42849bbae2078e34d3cc143
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22221751
DOI:10.1080/22221751.2022.2059401