دورية أكاديمية

NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls

التفاصيل البيبلوغرافية
العنوان: NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls
المؤلفون: Pavla Krotka, Katharina Hees, Peter Jacko, Dominic Magirr, Martin Posch, Marta Bofill Roig
المصدر: SoftwareX, Vol 23, Iss , Pp 101437- (2023)
بيانات النشر: Elsevier, 2023.
سنة النشر: 2023
المجموعة: LCC:Computer software
مصطلحات موضوعية: Statistics, Clinical trial simulation, Platform trials, Shared controls, Non-concurrent controls, Computer software, QA76.75-76.765
الوصف: Platform trials evaluate the efficacy of multiple treatments, allowing for late entry of the experimental arms and enabling efficiency gains by sharing controls. The power of individual treatment-control comparisons in such trials can be improved by utilizing non-concurrent controls (NCC) in the analysis. We present the R-package NCC for the design and analysis of platform trials using non-concurrent controls. NCC allows for simulating platform trials and evaluating the properties of analysis methods that make use of non-concurrent controls in a variety of settings. We describe the main NCC functions and show how to use the package to simulate and analyse platform trials by means of specific examples.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2352-7110
Relation: http://www.sciencedirect.com/science/article/pii/S2352711023001334; https://doaj.org/toc/2352-7110
DOI: 10.1016/j.softx.2023.101437
URL الوصول: https://doaj.org/article/904bebb8785243719aac4f0c30aa809f
رقم الأكسشن: edsdoj.904bebb8785243719aac4f0c30aa809f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23527110
DOI:10.1016/j.softx.2023.101437