دورية أكاديمية
A ten-year follow-up of human leptospirosis in Uruguay: an unresolved health problem
| العنوان: | A ten-year follow-up of human leptospirosis in Uruguay: an unresolved health problem |
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| المؤلفون: | Felipe Schelotto, Elba Hernández, Sabina González, Alicia Del Monte, Silvana Ifran, Karina Flores, Lorena Pardo, Daniel Parada, Mercedes Filippini, Victoria Balseiro, Juan Pablo Geymonat, Gustavo Varela |
| المصدر: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 54, Iss 2, Pp 69-76 (2012) |
| بيانات النشر: | Universidade de São Paulo (USP), 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Human leptospirosis, Bovine source, Rainfall, MAT, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Leptospira spp. are delicate bacteria that cannot be studied by usual microbiological methods. They cause leptospirosis, a zoonotic disease transmitted to humans through infected urine of wild or domestic animals. We studied the incidence of this disease in the Uruguayan population, its epidemiologic and clinical features, and compared diagnostic techniques. After examining 6,778 suspect cases, we estimated that about 15 infections/100,000 inhabitants occurred yearly, affecting mainly young male rural workers. Awareness about leptospirosis has grown among health professionals, and its lethality has consequently decreased. Bovine infections were probably the principal source of human disease. Rainfall volumes and floods were major factors of varying incidence. Most patients had fever, asthenia, myalgias or cephalalgia, with at least one additional abnormal clinical feature. 30-40% of confirmed cases presented abdominal signs and symptoms, conjunctival suffusion and altered renal or urinary function. Jaundice was more frequent in patients aged > 40 years. Clinical infections followed an acute pattern and their usual outcome was complete recovery. Laboratory diagnosis was based on indirect micro-agglutination standard technique (MAT). Second serum samples were difficult to obtain, often impairing completion of diagnosis. Immunofluorescence was useful as a screening test and for early detection of probable infections. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-9946 0036-4665 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652012000200003&lng=en&tlng=en; https://doaj.org/toc/1678-9946 |
| DOI: | 10.1590/S0036-46652012000200003 |
| URL الوصول: | https://doaj.org/article/c90cfd197f294862b44e83eb7d991f5d |
| رقم الأكسشن: | edsdoj.90cfd197f294862b44e83eb7d991f5d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16789946 00364665 |
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| DOI: | 10.1590/S0036-46652012000200003 |