دورية أكاديمية
CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION
| العنوان: | CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION |
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| المؤلفون: | Elizaveta S. Ageeva, Natalya V. Rymarenko, Elena N. Dyadyura, Anna K. Gurtovaya, Sergey L. Safronyuk, Remzie N. Ablaeva, Svetlana V. Usova |
| المصدر: | Siberian Journal of Life Sciences and Agriculture, Vol 15, Iss 6, Pp 246-266 (2023) |
| بيانات النشر: | Science and Innovation Center Publishing House, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Agriculture LCC:Science |
| مصطلحات موضوعية: | children, covid-19, lymphocytes, nk-lymphocytes, b-lymphocytes, Agriculture, Science |
| الوصف: | The article presents the results of the analysis of clinical and morphological characteristics and a number of indicators of peripheral blood in children with a new coronavirus infection. The purpose of the study is to give clinical and laboratory characteristics of the immune response in children with a new coronavirus infection. Materials and methods. 102 children with a new coronavirus infection were examined. Evaluation of peripheral blood parameters and lymphocyte subpopulations in children of three age groups 0-4 years, 5-9 years and 10-14 years. Results. In children with a new coronavirus infection, an imbalance of the granulocytic and lymphocytic link is observed, which is most pronounced for children of the younger (0-4 years) and middle (5-9 years) age groups. The general trend of changes is characterized by an increase in lymphocytes and granulocytes at the onset of the disease and a decrease after 2 weeks. The ratio of neutrophils to lymphocytes shows the predominance of neutrophils. Conclusion. The established changes are characterized as specific for most viral infections, but at the same time reflect the pathogenetic specifics of SARS-CoV-2 infection, as a combination of age-related features of the functioning of the immune system and the etiotropic effect of the virus. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Russian |
| تدمد: | 2658-6649 2658-6657 |
| Relation: | http://discover-journal.ru/jour/index.php/sjlsa/article/view/969; https://doaj.org/toc/2658-6649; https://doaj.org/toc/2658-6657 |
| DOI: | 10.12731/2658-6649-2023-15-6-969 |
| URL الوصول: | https://doaj.org/article/910b96c244a7434ea9823a4a3c21c955 |
| رقم الأكسشن: | edsdoj.910b96c244a7434ea9823a4a3c21c955 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26586649 26586657 |
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| DOI: | 10.12731/2658-6649-2023-15-6-969 |