دورية أكاديمية
Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke
| العنوان: | Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke |
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| المؤلفون: | Jason W. Siefferman, George Lai |
| المصدر: | Case Reports in Neurological Medicine, Vol 2015 (2015) |
| بيانات النشر: | Hindawi Limited, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Brain injury can lead to impaired cortical inhibition of the hypothalamus, resulting in increased sympathetic nervous system activation. Symptoms of paroxysmal sympathetic hyperactivity may include hyperthermia, tachycardia, tachypnea, vasodilation, and hyperhidrosis. We report the case of a 41-year-old man who suffered from a left middle cerebral artery stroke and subsequently developed central fever, contralateral temperature change, and hyperhidrosis. His symptoms abated with low-dose propranolol and then returned upon discontinuation. Restarting propranolol again stopped his symptoms. This represents the first report of propranolol being used for unilateral dysautonomia after stroke. Propranolol is a lipophilic nonselective beta-blocker which easily crosses the blood-brain barrier and may be used to treat paroxysmal sympathetic hyperactivity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-6668 2090-6676 |
| Relation: | https://doaj.org/toc/2090-6668; https://doaj.org/toc/2090-6676 |
| DOI: | 10.1155/2015/421563 |
| URL الوصول: | https://doaj.org/article/94ae2d8921f4428a983e379f9f6d5fbe |
| رقم الأكسشن: | edsdoj.94ae2d8921f4428a983e379f9f6d5fbe |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20906668 20906676 |
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| DOI: | 10.1155/2015/421563 |