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Protein-ligand binding interactions of imidazolium salts with SARS CoV-2

التفاصيل البيبلوغرافية
العنوان: Protein-ligand binding interactions of imidazolium salts with SARS CoV-2
المؤلفون: Dhurairaj Satheesh, Annamalai Rajendran, Kasi Chithra
المصدر: Heliyon, Vol 6, Iss 11, Pp e05544- (2020)
بيانات النشر: Elsevier, 2020.
سنة النشر: 2020
المجموعة: LCC:Science (General)
LCC:Social sciences (General)
مصطلحات موضوعية: Computational chemistry, Organic chemistry, Systems biology, Bioinformatics, Biotechnology, Biochemistry, Science (General), Q1-390, Social sciences (General), H1-99
الوصف: The disease called severe acute respiratory syndrome (SARS) is a lifestyle intimidating viral contamination affected by a positive, single stranded novel RNA virus (COVID-2019) from the enveloped coronaviruse family. The COVID-2019 virus has affected many people, scattering promptly, and researchers are attempting to find out medicines for its effectual cure in all over the globe. Chloroquine (ChQ) and its derivatives, an older drug used for the cure of malaria, is exposed to encompass a perceptible feasibility and commendable well-being in opposition to SARS CoV-2 associated pneumonia clinical trials conducted in China. Later on, a few investigations have been directed to find and present SARS CoV-2 antiviral medications. The aim of this present work deals with the potential binding interactions of some imidazolium salts with Nsp9 (Nonstructural protein 9) RNA binding protein of SARS CoV-2.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2405-8440
Relation: http://www.sciencedirect.com/science/article/pii/S2405844020323872; https://doaj.org/toc/2405-8440
DOI: 10.1016/j.heliyon.2020.e05544
URL الوصول: https://doaj.org/article/a9508d2483334593aab49c0a678e6573
رقم الأكسشن: edsdoj.9508d2483334593aab49c0a678e6573
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24058440
DOI:10.1016/j.heliyon.2020.e05544