دورية أكاديمية
أعرض في EDS

Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring

التفاصيل البيبلوغرافية
العنوان: Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring
المؤلفون: Hajar Abkhezr, Shirin Babri, Mahsa Farid Habibi, Fereshteh Farajdokht, Saeed Sadig-Etegad, Gisou Mohaddes
المصدر: Iranian Journal of Basic Medical Sciences, Vol 27, Iss 9, Pp 1115-1123 (2024)
بيانات النشر: Mashhad University of Medical Sciences, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
مصطلحات موضوعية: bdnf, corticosterone, elf-emf, prenatal stress, spatial memory, Medicine
الوصف: Objective(s): Prenatal stress (PS) can adversely affect cognitive and psychological functions in the offspring. This study aimed to determine the effect of PS and extremely low-frequency electromagnetic field (ELF-EMF) on spatial memory, serum corticosterone, brain-derived neurotrophic factor (BDNF) concentrations, and hippocampal BDNF levels in adult male offspring. Materials and Methods: Female Wistar rats were randomly divided into four groups (n=6): Control, Stress, ELF-EMF (exposure to ELF-EMF), and S+EMF (simultaneous exposure to stress and the ELF-EMF) groups. Animals received interven-tions for 21 days before and 21 days during pregnancy (a total of 42 days). On the offspring’s 90th postnatal day (PND), spatial memory was tested using Morris Water Maze, serum Corticosterone and BDNF levels were measured by the ELISA method, and hippocampal BDNF levels were measured by Western blotting. Results: PS did not affect spatial memory in the adult male offspring; however, it significantly (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2008-3866
2008-3874
Relation: https://ijbms.mums.ac.ir/article_24288_8395a4cccbe73b0ebb91779cbd27c55c.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874
DOI: 10.22038/ijbms.2024.75459.16357
URL الوصول: https://doaj.org/article/95f1558f380949969f329f238d61c7e1
رقم الأكسشن: edsdoj.95f1558f380949969f329f238d61c7e1
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20083866
20083874
DOI:10.22038/ijbms.2024.75459.16357