دورية أكاديمية

Evagination of cells controls bio-silica formation and maturation during spicule formation in sponges.

التفاصيل البيبلوغرافية
العنوان: Evagination of cells controls bio-silica formation and maturation during spicule formation in sponges.
المؤلفون: Xiaohong Wang, Matthias Wiens, Heinz C Schröder, Ute Schlossmacher, Dario Pisignano, Klaus Peter Jochum, Werner E G Müller
المصدر: PLoS ONE, Vol 6, Iss 6, p e20523 (2011)
بيانات النشر: Public Library of Science (PLoS), 2011.
سنة النشر: 2011
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: The enzymatic-silicatein mediated formation of the skeletal elements, the spicules of siliceous sponges starts intracellularly and is completed extracellularly. With Suberites domuncula we show that the axial growth of the spicules proceeds in three phases: (I) formation of an axial canal; (II) evagination of a cell process into the axial canal, and (III) assembly of the axial filament composed of silicatein. During these phases the core part of the spicule is synthesized. Silicatein and its substrate silicate are stored in silicasomes, found both inside and outside of the cellular extension within the axial canal, as well as all around the spicule. The membranes of the silicasomes are interspersed by pores of ≈ 2 nm that are likely associated with aquaporin channels which are implicated in the hardening of the initial bio-silica products formed by silicatein. We can summarize the sequence of events that govern spicule formation as follows: differential GENETIC READOUT (of silicatein) → FRACTAL ASSOCIATION of the silicateins → EVAGINATION of cells by hydro-mechanical forces into the axial canal → and finally PROCESSIVE BIO-SILICA POLYCONDENSATION around the axial canal. We termed this process, occurring sequentially or in parallel, BIO-INORGANIC SELF-ORGANIZATION.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC3107217?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0020523
URL الوصول: https://doaj.org/article/d96dd8686a85441caabe538ae62ac702
رقم الأكسشن: edsdoj.96dd8686a85441caabe538ae62ac702
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0020523