دورية أكاديمية
Serum irisin levels correlated to peritoneal dialysis adequacy in nondiabetic peritoneal dialysis patients.
العنوان: | Serum irisin levels correlated to peritoneal dialysis adequacy in nondiabetic peritoneal dialysis patients. |
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المؤلفون: | Zhijun Tan, Zengchun Ye, Jun Zhang, Yanru Chen, Cailian Cheng, Cheng Wang, Xun Liu, Tanqi Lou, Hui Peng |
المصدر: | PLoS ONE, Vol 12, Iss 4, p e0176137 (2017) |
بيانات النشر: | Public Library of Science (PLoS), 2017. |
سنة النشر: | 2017 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Irisin is a recently discovered myokine thought to be involved in multiple metabolism abnormalities in most dialysis patients. However, the myokine has not been thoroughly studied in peritoneal dialysis. This study aimed to evaluate serum irisin levels and establish their relation to dialysis adequacy, insulin resistance, and bone metabolism status in patients on peritoneal dialysis.A total of 59 nondiabetic prevalent peritoneal dialysis patients and 52 age- and sex-matched healthy controls were enrolled in this cross-sectional study. Serum irisin concentration was assessed by enzyme-linked immunosorbent assay. The correlations between serum irisin and dialysis adequacy, clinical, and metabolic variables were investigated.Serum irisin levels were lower in nondiabetic peritoneal dialysis patients (17.02ng/ml) compared with healthy controls (22.17ng/ml, P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 |
Relation: | http://europepmc.org/articles/PMC5406024?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0176137 |
URL الوصول: | https://doaj.org/article/96fc3164a3ef431fa807073bf860db0e |
رقم الأكسشن: | edsdoj.96fc3164a3ef431fa807073bf860db0e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 |
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DOI: | 10.1371/journal.pone.0176137 |