دورية أكاديمية
SRC-3, a Steroid Receptor Coactivator: Implication in Cancer
| العنوان: | SRC-3, a Steroid Receptor Coactivator: Implication in Cancer |
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| المؤلفون: | Licen Li, Chu-Xia Deng, Qiang Chen |
| المصدر: | International Journal of Molecular Sciences, Vol 22, Iss 9, p 4760 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | SRC-3, AIB1, coactivator, cancer, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Steroid receptor coactivator-3 (SRC-3), also known as amplified in breast cancer 1 (AIB1), is a member of the SRC family. SRC-3 regulates not only the transcriptional activity of nuclear receptors but also many other transcription factors. Besides the essential role of SRC-3 in physiological functions, it also acts as an oncogene to promote multiple aspects of cancer. This review updates the important progress of SRC-3 in carcinogenesis and summarizes its mode of action, which provides clues for cancer therapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/22/9/4760; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms22094760 |
| URL الوصول: | https://doaj.org/article/9789c7f80b034fcc826b1f95a2aacb7a |
| رقم الأكسشن: | edsdoj.9789c7f80b034fcc826b1f95a2aacb7a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms22094760 |