دورية أكاديمية
The incidence, risk factors and outcomes of impaired cerebral autoregulation in aortic arch surgery: a single-center, retrospective cohort study
| العنوان: | The incidence, risk factors and outcomes of impaired cerebral autoregulation in aortic arch surgery: a single-center, retrospective cohort study |
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| المؤلفون: | Ling Peng, Dan Guo, Yinhui Shi, Jiapei Yang, Wei Wei |
| المصدر: | Journal of Cardiothoracic Surgery, Vol 18, Iss 1, Pp 1-11 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Surgery LCC:Anesthesiology |
| مصطلحات موضوعية: | Cerebral autoregulation, Cardiopulmonary bypass, Hypothermia circulatory arrest, Near-infrared spectroscopy, Surgery, RD1-811, Anesthesiology, RD78.3-87.3 |
| الوصف: | Abstract Background Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its risks and associations with outcomes. The cerebral oximetry index (COx), which is a moving linear correlation coefficient between regional cerebral oxygen saturation (rScO2) and mean blood pressure (MAP), may reflect CA function. When COx approaches 1, it implies that CA is damaged, whereas the CA is functional when the COx value approaches 0. The objective of this study was to analyze the incidence and risks of impaired CA, based on COx assessment, in patients undergoing total aortic arch replacement under systemic moderate hypothermia and circulatory arrest of the lower body (MHCA). We also evaluated the association between impaired CA and patient outcomes. Methods One hundred and fifty-four adult patients who underwent total aortic arch replacement with stented elephant trunk implantation under MHCA at our hospital were retrospectively analyzed. Patients were defined as having new-onset impaired CA if pre-CPB COx 0.3. Pre- and intraoperative factors were tested for independent association with impaired CA. Postoperative outcomes were compared between patients with normal and impaired CA. Results In our 154 patients, 46(29.9%) developed new-onset impaired CA after CPB. Multivariable analysis revealed a prolonged low rScO2 (rScO2 |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1749-8090 |
| Relation: | https://doaj.org/toc/1749-8090 |
| DOI: | 10.1186/s13019-023-02413-z |
| URL الوصول: | https://doaj.org/article/e97c96388ff747a5950f970500ddbccf |
| رقم الأكسشن: | edsdoj.97c96388ff747a5950f970500ddbccf |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 17498090 |
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| DOI: | 10.1186/s13019-023-02413-z |