دورية أكاديمية
Prospective Study of Antibiotic Prophylaxis for Prostate Biopsy Involving >1100 Men
العنوان: | Prospective Study of Antibiotic Prophylaxis for Prostate Biopsy Involving >1100 Men |
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المؤلفون: | Rustom P. Manecksha, Gregory J. Nason, Ivor M. Cullen, Jérôme P. Fennell, Elizabeth McEvoy, Ted McDermott, Robert J. Flynn, Ronald Grainger, John A. Thornhill |
المصدر: | The Scientific World Journal, Vol 2012 (2012) |
بيانات النشر: | Hindawi Limited, 2012. |
سنة النشر: | 2012 |
المجموعة: | LCC:Technology LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Technology, Medicine, Science |
الوصف: | We aimed to compare infection rates for two 3-day antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy (TRUSgbp) and demonstrate local microbiological trends. In 2008, 558 men and, in 2009, 625 men had TRUSgpb. Regimen 1 (2008) comprised 400 mg Ofloxacin immediately before biopsy and 200 mg 12-hourly for 3 days. Regimen 2 (2009) comprised Ofloxacin 200 mg 12-hourly for 3 days commencing 24 hours before biopsy. 20/558 (3.6%) men had febrile episodes with regimen 1 and 10/625 (1.6%) men with regimen 2 (𝑃=0.03). E. coli was the most frequently isolated organism. Overall, 7/13 (54%) of positive urine cultures were quinolone resistant and (5/13) 40% were multidrug resistant. Overall, 5/9 (56%) patients with septicaemia were quinolone resistant. All patients were sensitive to Meropenem. There was 1 (0.2%) death with regimen 1. Commencing Ofloxacin 24 hours before TRUSgpb reduced the incidence of febrile episodes significantly. We observed the emergence of quinolone and multidrug-resistant E. coli. Meropenem should be considered for unresolving sepsis. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1537-744X |
Relation: | https://doaj.org/toc/1537-744X |
DOI: | 10.1100/2012/650858 |
URL الوصول: | https://doaj.org/article/97f304968a7248009bb895690d9a841e |
رقم الأكسشن: | edsdoj.97f304968a7248009bb895690d9a841e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 1537744X |
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DOI: | 10.1100/2012/650858 |