دورية أكاديمية
Chiral Ionic Liquids Based on l-Cysteine Derivatives for Asymmetric Aldol Reaction
| العنوان: | Chiral Ionic Liquids Based on l-Cysteine Derivatives for Asymmetric Aldol Reaction |
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| المؤلفون: | Karolina Zalewska, Małgorzata E. Zakrzewska, Luis C. Branco |
| المصدر: | Catalysts, Vol 12, Iss 1, p 47 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Chemical technology LCC:Chemistry |
| مصطلحات موضوعية: | asymmetric catalysis, aldol reactions, cysteine derivatives, chiral ionic liquids, organocatalysts, Chemical technology, TP1-1185, Chemistry, QD1-999 |
| الوصف: | Structure, and consequently properties, of ionic liquids can be easily tailored by changing cation/anion combinations and/or attaching functional groups. By grafting enantiopure moieties to the framework of ionic liquid it is possible to prepare bioinspired chiral molecules that can serve as a reaction medium, additive or even asymmetric catalyst. In this context, new chiral ionic liquids (CILs), based on biomolecules, such as aminoacids (l-Cysteine derivatives), have been synthesised and tested in asymmetric aldol condensation of aldehydes and ketones. The best results were obtained for CILs composed of S-methyl-l-cysteine cation and bis(trifluoromethane)sulfonimide anion, in the reaction of 2- or 4-nitrobenzaldehyde with acetone or cyclohexanone, giving the aldol product in moderate yields 70–76% and high ee values (up to 96%). |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2073-4344 |
| Relation: | https://www.mdpi.com/2073-4344/12/1/47; https://doaj.org/toc/2073-4344 |
| DOI: | 10.3390/catal12010047 |
| URL الوصول: | https://doaj.org/article/98340bc9d330427d9991cc05ca98413b |
| رقم الأكسشن: | edsdoj.98340bc9d330427d9991cc05ca98413b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20734344 |
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| DOI: | 10.3390/catal12010047 |