دورية أكاديمية
Effect of 8 weeks resistance training on sphingosine-1-phosphate level and gene expression of SK1 enzyme, isoforms of MHCs in skeletal muscles of male Wistar Rats
| العنوان: | Effect of 8 weeks resistance training on sphingosine-1-phosphate level and gene expression of SK1 enzyme, isoforms of MHCs in skeletal muscles of male Wistar Rats |
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| المؤلفون: | Banitalebi E (PhD), Ghatre Samani K (PhD), Mardani G (MSc), Soheili A (Pharm.D), Ansari Samani R (MSc), Teimori H (PhD) |
| المصدر: | مجله دانشگاه علوم پزشکی گرگان, Vol 14, Iss 4, Pp 44-51 (2012) |
| بيانات النشر: | Golestan University of Medical Sciences, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | Resistance training, Sphingosine-1-phosphate (S1P), Sphingosine-1-phosphate Kinase 1 (SK1), Myosine heavy chain (MHC), Fast-twitch and slow twitch muscles, Medicine, Medicine (General), R5-920 |
| الوصف: | Background and Objective: Sphingosine-1-phosphate (S1P) is involved in regulation of proliferation, differentiation, hypertrophy and anti-apoptosis and activation of satellite cells. This study was done to evaluated the effect of 8 weeks resistance training on sphingosine-1-phosphate level and gene expression of SK1 enzyme, isoforms of MHCs in skeletal muscles of male Wistar rats. Materials and Methods: This experimental study was done on Twenty four 8-week-old 190-250 gr male Wistar rats. The rats were allocated randomly into control (N=12) and training (N=12) groups. Resistance training was done using a 1 meter height ladder with 2 cm grid with an 85 degree incline, and weights attached to rat's tails. The content of S1P present in the chloroform layer was determined by means of high performance liquid chromatography (HPLC). Determination of relative mRNA expression was performed by Real-time PCR. Data were analyzed using SPSS-17, Kolmogorov-Smirnov and independent t-test. Results: Resistance exercise training increased the total content of S1P in FHL (fast-twitch) and soleus (slow-twitch) muscles in comparison with control group (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Persian |
| تدمد: | 1562-4765 2008-4080 |
| Relation: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-638&slc_lang=en&sid=1; https://doaj.org/toc/1562-4765; https://doaj.org/toc/2008-4080 |
| URL الوصول: | https://doaj.org/article/9891ca6e4ac845f79dd329f19fe687a1 |
| رقم الأكسشن: | edsdoj.9891ca6e4ac845f79dd329f19fe687a1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15624765 20084080 |
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